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迈向联合国艾滋病规划署快速通道目标:在津巴布韦确定艾滋病毒预防和护理的重点地域。

Towards UNAIDS Fast-Track goals: targeting priority geographic areas for HIV prevention and care in Zimbabwe.

机构信息

Deparment of Geography and Geographic Information Science.

Health Geography and Disease Modeling Laboratory, University of Cincinnati, Cincinnati, Ohio, USA.

出版信息

AIDS. 2019 Feb 1;33(2):305-314. doi: 10.1097/QAD.0000000000002052.

Abstract

INTRODUCTION

Zimbabwe has made substantial progress towards the Joint United Nations Programme on HIV/AIDS (UNAIDS) targets of 90-90-90 by 2020, with 73% of people living with HIV diagnosed, 87% of those diagnosed on antiretroviral therapy (ART) and 86% of those on ART virally suppressed. Despite this exceptional response, more effort is needed to completely achieve the UNAIDS targets. Here, we conducted a detailed spatial analysis of the geographical structure of the HIV epidemic in Zimbabwe to include geographical prioritization as a key component of their overall HIV intervention strategy.

METHODS

Data were obtained from Zimbabwe Demographic and Health Survey (ZDHS) conducted in 2015 as well as estimations from the Zimbabwe Population-Based HIV Impact Assessment (ZIMPHIA) 2016 report, and other published literature. Data were used to produce high-resolution maps of HIV prevalence. Using these maps combined with the population density maps, we mapped the HIV-infected population lacking ART coverage and viral suppression.

RESULTS

HIV maps for both sexes illustrated similar geographical variation of HIV prevalence within the country. HIV-infected populations lacking ART coverage and viral suppression were concentrated in the main cities and urban settlements such as Bulawayo, Harare, Ruwa and Chitungwiza.

CONCLUSION

Our study showed extensive local variation in HIV disease burden across Zimbabwe for both women and men. The high-resolution maps generated here identified areas wherein high density of HIV-infected individuals are lacking ART coverage and viral suppression. These results suggest that there is need to tailor HIV programmes to address specific local needs to efficiently achieve epidemic control in Zimbabwe.

摘要

简介

津巴布韦在实现联合国艾滋病规划署(UNAIDS)2020 年 90-90-90 目标方面取得了重大进展,有 73%的艾滋病毒感染者得到诊断,87%的诊断者接受了抗逆转录病毒治疗(ART),86%的接受 ART 治疗者病毒得到抑制。尽管取得了这一非凡的成就,但仍需付出更多努力才能完全实现 UNAIDS 的目标。在此,我们对津巴布韦艾滋病毒流行的地理结构进行了详细的空间分析,将地理优先排序作为其整体艾滋病毒干预策略的一个关键组成部分。

方法

数据来自 2015 年津巴布韦人口与健康调查(ZDHS)以及 2016 年津巴布韦基于人口的艾滋病毒影响评估(ZIMPHIA)报告和其他已发表文献中的估计数据。数据用于制作艾滋病毒流行率的高分辨率地图。利用这些地图结合人口密度地图,我们绘制了缺乏抗逆转录病毒治疗覆盖和病毒抑制的艾滋病毒感染者地图。

结果

针对男女的艾滋病毒地图均显示了该国艾滋病毒流行率的相似地理变化。缺乏抗逆转录病毒治疗覆盖和病毒抑制的艾滋病毒感染者集中在主要城市和城市定居点,如布拉瓦约、哈拉雷、鲁瓦和奇通圭扎。

结论

我们的研究表明,津巴布韦男女的艾滋病毒疾病负担存在广泛的局部差异。这里生成的高分辨率地图确定了缺乏抗逆转录病毒治疗覆盖和病毒抑制的高感染密度人群区域。这些结果表明,需要调整艾滋病毒规划以满足特定的地方需求,以有效控制津巴布韦的疫情。

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