Morita Hiromitsu, Imai Yuko, Yoneda Masahiro, Hirofuji Takao
Section of General Dentistry, Department of General Dentistry, Fukuoka, Japan.
Special Patient Oral Care Unit, Kyushu University Hospital, Fukuoka, Japan.
Spec Care Dentist. 2017 Jan;37(1):43-46. doi: 10.1111/scd.12190. Epub 2016 Jun 30.
Bisphosphonates and irradiation are useful medical treatments, but can often cause oral complications such as medication-related oral necrosis of the jaw (MRONJ) and osteoradionecrosis (ORN) during oral surgery, including tooth extraction. Therefore, we should take all risks into consideration carefully before choosing dental treatment for patients with a medical history of such therapies. A 55-year-old woman who underwent cord blood transplantation to treat extranodal natural killer T (NK/T) cell lymphoma (nasal type IVB) had a medical history of bisphosphonate and irradiation treatments. We treated her residual tooth root by applying orthodontic extrusion to avoid extraction and successfully restored the tooth. Application of an orthodontic tooth extrusion technique for conservative treatment of a residual tooth is a useful means of avoiding MRONJ or ORN in patients who have a medical history of bisphosphonate and irradiation treatments.
双膦酸盐和放射治疗是有效的医学治疗方法，但在包括拔牙在内的口腔手术过程中，常常会引发口腔并发症，如药物相关性颌骨坏死（MRONJ）和放射性骨坏死（ORN）。因此，在为有此类治疗病史的患者选择牙科治疗前，我们应仔细考虑所有风险。一名55岁女性因治疗结外自然杀伤T（NK/T）细胞淋巴瘤（鼻型IVB）接受了脐带血移植，有双膦酸盐和放射治疗病史。我们通过正畸牵引的方法治疗了她的残根，避免了拔牙，并成功修复了牙齿。应用正畸牙齿牵引技术保守治疗残根，是避免有双膦酸盐和放射治疗病史患者发生MRONJ或ORN的有效方法。
