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使用CTA对心内解剖结构进行三维重建及法洛四联症的手术规划:三级先天性心脏病中心的早期经验

Three-Dimensional Reconstruction of Intracardiac Anatomy Using CTA and Surgical Planning for Double Outlet Right Ventricle: Early Experience at a Tertiary Care Congenital Heart Center.

作者信息

Dydynski Philip B, Kiper Carmen, Kozik Deborah, Keller Bradley B, Austin Erle, Holland Brian

机构信息

Department of Pediatric Radiology, Kosair Children's Hospital, Norton Healthcare, Louisville, KY, USA

Department of Pediatrics, University of Louisville, Louisville, KY, USA.

出版信息

World J Pediatr Congenit Heart Surg. 2016 Jul;7(4):467-74. doi: 10.1177/2150135116651399.

DOI:10.1177/2150135116651399
PMID:27358302
Abstract

BACKGROUND

Although transthoracic echocardiography (TTE) routinely establishes the diagnosis of double outlet right ventricle (DORV), it can be suboptimal for depicting exact ventricular septal defect (VSD) position, especially with respect to the outflow tracts. Advanced imaging with computed tomography angiography (CTA) can help visualize structures and relationships not easily seen by echo. Using computer-aided design, we have the ability to create three-dimensional (3D) models of the intracardiac anatomy, which can be helpful for better depicting the overall anatomy to assist surgical planning.

METHODS

Patients with a diagnosis of DORV were retrospectively reviewed at our institution from October 2013 to April 2015. Patients who preoperatively underwent both TTE and CTA with 3D reconstruction of the intracardiac anatomy were included. Computed tomography angiography findings with 3D intracardiac model creation were compared to the surgical findings.

RESULTS

Twenty-five patients underwent surgical repair of DORV during the study period. Five patients had CTA with 3D reconstruction, in addition to the standard TTE images, and were included in the study. In all five cases, CTA with 3D reconstruction of the intracardiac anatomy accurately depicted the VSD position relative to important adjacent structures, including the outflow tracts.

CONCLUSION

Three-dimensional reconstruction of the intracardiac anatomy using CTA data can provide accurate data for presurgical planning of DORV repair and has the potential for being especially useful in patients for whom intracardiac anatomy and VSD position cannot be well seen by TTE. A larger prospective analysis is warranted to help validate this approach.

摘要

背景

虽然经胸超声心动图(TTE)通常能确诊右心室双出口(DORV),但在描绘室间隔缺损(VSD)的确切位置时可能并不理想,尤其是相对于流出道而言。计算机断层血管造影(CTA)的先进成像有助于显示超声不易观察到的结构和关系。利用计算机辅助设计,我们有能力创建心脏内解剖结构的三维(3D)模型,这有助于更好地描绘整体解剖结构以辅助手术规划。

方法

对2013年10月至2015年4月在我院诊断为DORV的患者进行回顾性研究。纳入术前同时接受TTE和心脏内解剖结构3D重建CTA检查的患者。将CTA检查结果及创建的3D心脏内模型与手术结果进行比较。

结果

在研究期间,25例患者接受了DORV手术修复。除标准TTE图像外,5例患者还接受了CTA及3D重建,并纳入研究。在所有5例病例中,心脏内解剖结构的CTA 3D重建准确描绘了VSD相对于重要相邻结构(包括流出道)的位置。

结论

利用CTA数据进行心脏内解剖结构的三维重建可为DORV修复的术前规划提供准确数据,对于TTE无法清晰显示心脏内解剖结构和VSD位置的患者可能特别有用。有必要进行更大规模的前瞻性分析以验证这种方法。

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