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2002年至2011年波德卡尔帕希省年轻女性人群中乳腺癌的发病率。

The incidence of breast cancer in population of young women from Podkarpackie province in 2002-2011.

作者信息

Radziszewska Aneta U, Karczmarek-Borowska Bożenna, Grądalska-Lampart Monika, Filip Agata A

机构信息

Department of Epidemiology and Podkarpackie Cancer Registry, Podkarpackie Oncology Centre, Rzeszow, Poland.

Department of Oncology, Faculty of Medical Sciences, University of Rzeszow, Rzeszow, Poland.

出版信息

Contemp Oncol (Pozn). 2016;20(2):176-84. doi: 10.5114/wo.2016.60070. Epub 2016 Jun 14.

Abstract

INTRODUCTION

Breast cancer (BC) in young women of Podkarpackie province accounts for approximately 11.0% of all diagnosed breast tumors.

AIM OF THE STUDY

Aim of the study was to assess the trends in incidence of BC among women younger than 44 from Podkarpackie in the years 2002-2011.

MATERIAL AND METHODS

614 cases of malignant BC and 26 cases of cancer in situ were analyzed. The crude and the standardized incidence ratios were estimated; the percentage of histopathologically confirmed cancer cases and the percentage share of registered malignant breast tumors were calculated. The analysis of incidence in individual counties was also presented, as well as the stages of clinical advancement at diagnosis and the methods of treatment.

RESULTS

The number of registered cases at 2011 was 73, and it was 37.7% higher as compared to 2002. During the period analyzed, the increase in the crude and the standardized cancer incidence ratios was observed. The percentage share of BC in the examined group increased of 5.4% in 2011. Significant variation in incidence among different counties was observed. The incidence ratios ranged from 65.8 to 93.1/100 000. BC in young women most commonly was diagnosed as locally advanced and over 70% of patients were radically treated.

CONCLUSIONS

Even though the progress in diagnostics and treatment has been made, BC in young women is diagnosed later than it should be and at considerably advanced stage. It is relevant to propagate the knowledge among women and health professionals to emphasize that BC may affect young women.

摘要

引言

在喀尔巴阡省,年轻女性乳腺癌(BC)约占所有确诊乳腺肿瘤的11.0%。

研究目的

本研究旨在评估2002 - 2011年期间喀尔巴阡省44岁以下女性乳腺癌的发病趋势。

材料与方法

分析了614例恶性乳腺癌病例和26例原位癌病例。估算了粗发病率和标准化发病率;计算了组织病理学确诊癌症病例的百分比以及登记的恶性乳腺肿瘤的百分比。还展示了各县发病率的分析情况,以及诊断时的临床进展阶段和治疗方法。

结果

2011年登记病例数为73例,比2002年高出37.7%。在分析期间,观察到粗发病率和标准化癌症发病率有所上升。2011年,所检查组中乳腺癌的百分比增加了5.4%。不同县之间的发病率存在显著差异。发病率范围为65.8至93.1/100 000。年轻女性乳腺癌最常被诊断为局部晚期,超过70%的患者接受了根治性治疗。

结论

尽管在诊断和治疗方面取得了进展,但年轻女性乳腺癌的诊断仍比应有的时间晚,且处于相当晚期。向女性和卫生专业人员传播相关知识,强调乳腺癌可能影响年轻女性,这一点很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b55/4925735/48038e817d9e/WO-20-27629-g001.jpg

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