Tanaka M, Yamakawa M, Watahiki M, Yamamoto M, Nakashima K
Department of Biochemistry, Mie University School of Medicine, Japan.
Biochim Biophys Acta. 1989 Jul 7;1008(2):193-7. doi: 10.1016/0167-4781(80)90008-1.
A novel cDNA clone that hybridized to bovine prolactin cDNA was isolated from a bovine (Bos taurus) placental cDNA library and the nucleotide sequence was analyzed. The cDNA clone, named bPLP-III, contained one open reading frame encoding a protein consisting of 239 amino acids. The amino-acid sequence of bPLP-III is 43 and 57% homologous to bovine preprolactin and a bovine prolactin-related protein, bPRC-I, respectively, but only 23% homologous to bovine pregrowth hormone. The predicted mature protein of bPLP-III is distinct from bovine placental lactogens in amino-acid composition, suggesting that bPLP-III is the clone for a new member of prolactin-related mRNA expressed in bovine placenta.
