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Three cases of OXA-48-like carbapenemase producing Enterobacteriaceae (not) detected using Xpert Carba-R.

作者信息

Boelens Jerina, Yusuf Erlangga, Decruyenaere Johan, Coorevits Liselotte, Piérard Denis, Claeys Geert

机构信息

a Department of Laboratory Medicine , Ghent University Hospital , Ghent , Belgium.

b Department of Microbiology and Infection Control , UZ Brussel (Brussels University Hospital) , Brussels , Belgium.

出版信息

Acta Clin Belg. 2017 Aug;72(4):242-244. doi: 10.1080/17843286.2016.1198520. Epub 2016 Jun 17.

Abstract

The increasing prevalence of carbapenemase-producing Enterobacteriaceae necessitates laboratories to invest in the detection of these bacteria, both with phenotypic and to a lesser extent molecular methods. OXA-48-like strains are rapidly emerging, especially in Europe. Since the expression level of OXA-48 is low and some strains present with several alleles, some types might be missed by some molecular assays. Three cases of OXA-48-like strains are described here, where the detection was not straightforward.

摘要

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