El-Ghareeb Azza S, Waked Neveen M, Al-Feky Hala M
J Egypt Soc Parasitol. 2016 Apr;46(1):9-18. doi: 10.12816/0026145.
A cross sectional study compared the clinical features of the pulmonary and hepatic hydatid cysts in children and adults and evaluated IHAT and ELISA techniques in diagnosis. The results showed that the patients ages were 5-14 years (10.6 ± 3.7) in children and 16-75 years (32.2 ± 14) in adults, patients 34 (75.5%) had liver cysts, 25 (55.5%) had pulmonary cysts and 7 (15.5%) had both liver and lung cysts. In hepatic hydatidosis, 7/34 (20.5%) cases were asymptomatic while others showed variable clinical manifestations. The commonest symptom was localized right hypochondrial pain in 13 (38.2%) and the least one was jaundice in 4 (11.7%). The commonest sign was abdominal masses on the right hypochondrium in 88.2% and the least one was ascites in 5.8%.The commonest symptom of pulmonary hydatidosis was chest pain in 8 (34.7%) followed by cough and hemoptysis pn 4 (17.3%) and the least one was cough and fever (8.6%). Pulmonary hydatid cysts in children were significantly higher in males (17.3%) than females (4.3%), but without significance in adults (26% in male vs. 21.7% in females). Sex difference in hydatid cyst frequencies between adults and children was significant (P < 0.05). Mixed hepatic and pulmonary cysts were less in children than in adults (14.3% vs. 85.7%), with huge pulmonary cysts of 20 cm were more common in children (37.7%) than in adults (17.7%). The high sensitivity (95.5%) of ELISA-IgG recommended this test showed a dependable sero-diagnosing one.
一项横断面研究比较了儿童和成人肺及肝包虫囊肿的临床特征，并评估了间接血凝试验（IHAT）和酶联免疫吸附测定（ELISA）技术在诊断中的应用。结果显示，儿童患者年龄为5至14岁（10.6±3.7），成人患者年龄为16至75岁（32.2±14）。34例（75.5%）患者有肝囊肿，25例（55.5%）有肺囊肿，7例（15.5%）既有肝囊肿又有肺囊肿。在肝包虫病中，7/34例（20.5%）无症状，其他患者表现出不同的临床表现。最常见的症状是右上腹局部疼痛，共13例（38.2%），最少见的症状是黄疸，共4例（11.7%）。最常见的体征是右季肋部腹部肿块，占88.2%，最少见的体征是腹水，占5.8%。肺包虫病最常见的症状是胸痛，共8例（34.7%），其次是咳嗽和咯血，共4例（17.3%），最少见的症状是咳嗽和发热，占8.6%。儿童肺包虫囊肿男性（17.3%）明显高于女性（4.3%），但成人中无显著差异（男性26%，女性21.7%）。成人与儿童包虫囊肿发生率的性别差异具有统计学意义（P<0.05）。儿童肝肺混合囊肿少于成人（14.3%对85.7%），直径达20厘米的巨大肺囊肿在儿童中（37.7%）比成人中（17.7%）更常见。ELISA-IgG的高敏感性（95.5%）表明该检测是一种可靠的血清学诊断方法。
