Suppr超能文献

15000名男性和女性的不孕患病率及寻求帮助情况。

Prevalence of infertility and help seeking among 15 000 women and men.

作者信息

Datta J, Palmer M J, Tanton C, Gibson L J, Jones K G, Macdowall W, Glasier A, Sonnenberg P, Field N, Mercer C H, Johnson A M, Wellings K

机构信息

Centre for Sexual and Reproductive Health Research, Department of Social and Environmental Health Research, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London WC1H 9SH, UK

Centre for Sexual and Reproductive Health Research, Department of Social and Environmental Health Research, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London WC1H 9SH, UK.

出版信息

Hum Reprod. 2016 Sep;31(9):2108-18. doi: 10.1093/humrep/dew123. Epub 2016 Jun 30.

Abstract

STUDY QUESTION

What is the prevalence of infertility and of help seeking among women and men in Britain?

SUMMARY ANSWER

One in eight women and one in ten men aged 16-74 years had experienced infertility, defined by unsuccessfully attempting pregnancy for a year or longer, and little more than half of these people sought medical or professional help.

WHAT IS KNOWN ALREADY

Estimates of infertility and help seeking in Britain vary widely and are not easily comparable because of different definitions and study populations.

STUDY DESIGN, SIZE, DURATION: A cross-sectional population survey was conducted between 2010 and 2012 with a sample of 15 162 women and men aged 16-74 years.

PARTICIPANTS/MATERIALS, SETTING, METHODS: Participants completed the Natsal-3 questionnaire, using computer-assisted personal interviewing (CAPI) and computer-assisted self-interview (CASI).

MAIN RESULTS AND THE ROLE OF CHANCE

The reported prevalence of infertility was 12.5% (CI 95% 11.7-13.3) among women and 10.1% (CI 95% 9.2-11.1) among men. Increased prevalence was associated with later cohabitation with a partner, higher socio-economic status and, for those who had a child, becoming parents at older ages. The reported prevalence of help seeking was 57.3% (CI 95% 53.6-61.0) among women and 53.2% (CI 95% 48.1-58.1) among men. Help seekers were more likely to be better educated and in higher status occupations and, among those who had a child, to have become parents later in life.

LIMITATIONS, REASONS FOR CAUTION: These data are cross-sectional so it is not possible to establish temporality or infer causality. Self-reported data may be subject to recall bias.

WIDER IMPLICATIONS OF THE FINDINGS

The study provides estimates of infertility and help seeking in Britain and the results indicate that the prevalence of infertility is higher among those delaying parenthood. Those with higher educational qualifications and occupational status are more likely to consult with medical professionals for fertility problems than others and these inequalities in help seeking should be considered by clinical practice and public health.

STUDY FUNDING/COMPETING INTERESTS: Funding was provided by grants from the Medical Research Council and the Wellcome Trust, with support from the Economic and Social Research Council and the Department of Health. AMJ is a Governor of the Wellcome Trust. Other authors have no competing interests.

摘要

研究问题

英国男性和女性的不孕不育患病率以及寻求帮助的情况如何?

总结答案

在16 - 74岁的女性中,每八人中有一人经历过不孕不育,即尝试怀孕一年或更长时间未成功;在男性中,这一比例为十分之一。而这些人中只有略多于一半的人寻求过医疗或专业帮助。

已知信息

由于定义和研究人群不同,英国对不孕不育及寻求帮助情况的估计差异很大,且不易比较。

研究设计、规模、持续时间:2010年至2012年进行了一项横断面人口调查,样本为15162名16 - 74岁的男性和女性。

参与者/材料、环境、方法:参与者通过计算机辅助个人访谈(CAPI)和计算机辅助自我访谈(CASI)完成了国民性态度和生活方式调查(Natsal - 3)问卷。

主要结果及机遇的作用

报告的女性不孕不育患病率为12.5%(95%置信区间11.7 - 13.3),男性为10.1%(95%置信区间9.2 - 11.1)。患病率增加与与伴侣较晚同居、较高的社会经济地位有关,对于那些已有孩子的人来说,与较晚成为父母有关。报告的寻求帮助的患病率女性为57.3%(95%置信区间53.6 - 61.0),男性为53.2%(95%置信区间48.1 - 58.1)。寻求帮助者更有可能受教育程度更高、从事地位更高的职业,并且在那些已有孩子的人中,更有可能在晚年成为父母。

局限性、谨慎原因:这些数据是横断面数据,因此无法确定时间顺序或推断因果关系。自我报告的数据可能存在回忆偏差。

研究结果的更广泛影响

该研究提供了英国不孕不育及寻求帮助情况的估计,结果表明在推迟生育的人群中不孕不育患病率更高。与其他人相比,具有较高学历和职业地位的人更有可能就生育问题咨询医疗专业人员,临床实践和公共卫生应考虑这些在寻求帮助方面的不平等现象。

研究资金/利益冲突:资金由医学研究理事会和惠康信托基金会的拨款提供,经济和社会研究理事会以及卫生部提供支持。AMJ是惠康信托基金会的理事。其他作者无利益冲突。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d24/4991655/b9142ee7ec7e/dew12301.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验