Lakshmi Chintamaneni Raja, Bhavana Sujana Mulk, Nallamilli Sai Madhavi, Prabhat Meka Poorna Venkata, Sarat Gummadapu, Anuradha Chennupati
Department of Oral Medicine and Radiology, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Gannavaram Mandal, Krishna District, Andhra Pradesh, India.
Iran J Med Sci. 2016 Jul;41(4):340-4.
Ameloblastomas are slow growing, locally invasive, benign odontogenic tumors of an epithelial origin, accounting for approximately 1% of all oral tumors. A 40-year-old man presented with a chief complaint of a swelling over the left side of his face of 4 years' duration. On examination, gross facial asymmetry was detected, and a well-defined swelling was noted intraorally involving the left maxilla medially from the mid palatal raphe and obliterating the buccal vestibule laterally. The swelling was non-tender and exhibited dual consistencies: firm in the palate and cystic in the vestibular region. Computed tomography revealed a multilocular radiolucency, which involved the left maxilla, encroached into the left maxillary sinus and the nasal complex, and caused bony erosion. Early diagnosis and treatment are the key tools in managing ameloblastomas, failure of which may lead to a significant deterioration of the prognosis and an increased recurrence rate. Uncommon variants of ameloblastomas have been gaining interest recently. To date, 25 cases of hybrid ameloblastomas have been documented in the scientific literature. We present an extremely rare hybrid type of the ameloblastoma with combined follicular, cystic, acanthomatous, and desmoplastic variants, which render it the first of its kind to have ever been reported.
成釉细胞瘤是一种生长缓慢、具有局部侵袭性的上皮源性良性牙源性肿瘤，约占所有口腔肿瘤的1%。一名40岁男性，主诉左侧面部肿胀4年。检查发现面部明显不对称，口腔内可见界限清楚的肿胀，累及左侧上颌骨，起自腭中缝内侧，向外使颊侧前庭消失。肿胀无压痛，质地不均：腭部质地硬，前庭区呈囊性。计算机断层扫描显示多房性透射区，累及左侧上颌骨，侵犯左侧上颌窦和鼻腔结构，并导致骨质侵蚀。早期诊断和治疗是处理成釉细胞瘤的关键，否则可能导致预后显著恶化和复发率增加。成釉细胞瘤的罕见变异型近来受到关注。迄今为止，科学文献中已记录了25例混合性成釉细胞瘤。我们报告了一种极其罕见的混合型成釉细胞瘤，具有滤泡型、囊性、棘皮瘤型和促结缔组织增生型的联合变异，这使其成为首例被报道的此类病例。
