血糖控制对结肠镜检查结果的影响：肠道准备和息肉检测。
Impact of glycemic control on colonoscopy outcomes: bowel preparation and polyp detection.
作者信息
Izzy Manhal, Changela Kinesh, Alhankawi Dhuha, Haeri Nami Safai, Shah Sulay, Jibara Ghalib, Anand Sury, Singhal Shashideep
机构信息
Division of Gastroenterology and Hepatology, Montefiore Medical Center, Bronx, NY (Manhal Izzy); Division of Gastroenterology, The Brooklyn Hospital Center, Brooklyn, NY (Manhal Izzy, Kinesh Changela, Dhuha Alhankawi, Nami Safai Haeri, Sury Anand).
Division of Gastroenterology, The Brooklyn Hospital Center, Brooklyn, NY (Manhal Izzy, Kinesh Changela, Dhuha Alhankawi, Nami Safai Haeri, Sury Anand).
出版信息
Ann Gastroenterol. 2016 Jul-Sep;29(3):332-5. doi: 10.20524/aog.2016.0060. Epub 2016 Mar 3.
BACKGROUND
The negative effect of diabetes mellitus (DM) on the colonoscopy preparation has been previously established. Metabolic syndrome has been shown to increase risk for malignancy and possibly for premalignant lesions. This study aimed to investigate the impact of DM control on colonoscopy outcomes including bowel preparation and adenoma detection rate (ADR).
METHODS
We included patients with DM who underwent colonoscopy in our hospital and had a documented glycated hemoglobin (HbA1C) within 3 months. Patients were categorized into three groups based on their HbA1C level. The clinical and endoscopic data were collected and analyzed.
RESULTS
Our cohort included 352 DM patients. The mean age was 63.5 years. When patients were analyzed based on HBA1C, bowel preparation was poor in 46.7% of patients with good glycemic control, 52.1% of patients with fair control and 50% of patients with poor control. ADR was 24.3% in patients with good glycemic control, 20.2% in patients with fair glycemic control and 27.1% in patients with poor glycemic control. There was no statistically significant difference in the quality of preparation or adenoma detection amongst the groups.
CONCLUSION
The degree of glycemic control did not impact the quality of bowel preparation or ADR.
背景
糖尿病（DM）对结肠镜检查准备工作的负面影响此前已得到证实。代谢综合征已被证明会增加患恶性肿瘤以及可能的癌前病变的风险。本研究旨在调查糖尿病控制对结肠镜检查结果的影响，包括肠道准备情况和腺瘤检出率（ADR）。
方法
我们纳入了在我院接受结肠镜检查且在3个月内有糖化血红蛋白（HbA1C）记录的糖尿病患者。根据HbA1C水平将患者分为三组。收集并分析临床和内镜数据。
结果
我们的队列包括352例糖尿病患者。平均年龄为63.5岁。根据HbA1C对患者进行分析时，血糖控制良好的患者中46.7%肠道准备不佳，血糖控制一般的患者中52.1%肠道准备不佳，血糖控制差的患者中50%肠道准备不佳。血糖控制良好的患者腺瘤检出率为24.3%，血糖控制一般的患者为20.2%，血糖控制差的患者为27.1%。各组之间在准备质量或腺瘤检出方面无统计学显著差异。
结论
血糖控制程度不影响肠道准备质量或腺瘤检出率。
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