一例由高毒力大肠杆菌菌株引起的坏死性筋膜炎致死病例。
A Fatal Case of Necrotizing Fasciitis Caused by a Highly Virulent Escherichia coli Strain.
作者信息
Bekal Sadjia, Vincent André, Lin Alex, Harel Josée, Côté Jean-Charles, Tremblay Cécile
机构信息
Laboratoire de Santé Publique du Québec, Sainte-Anne-de-Bellevue, QC, Canada H9X 3R5; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC, Canada H3T 1J4.
Centre Hospitalier Affilié Universitaire, Hôtel-Dieu de Lévis, Lévis, QC, Canada G6V 3Z1.
出版信息
Can J Infect Dis Med Microbiol. 2016;2016:2796412. doi: 10.1155/2016/2796412. Epub 2016 May 31.
Abstract
Necrotizing fasciitis is a serious disease characterized by the necrosis of the subcutaneous tissues and fascia. E. coli as the etiologic agent of necrotizing fasciitis is a rare occurrence. A 66-year-old woman underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. She rapidly developed necrotizing fasciitis which led to her death 68 hours following surgery. An E. coli strain was isolated from blood and fascia cultures. DNA microarray revealed the presence of 20 virulence genes.
摘要
坏死性筋膜炎是一种以皮下组织和筋膜坏死为特征的严重疾病。大肠杆菌作为坏死性筋膜炎的病原体较为罕见。一名66岁女性接受了全腹子宫切除术及双侧输卵管卵巢切除术。术后她迅速发展为坏死性筋膜炎，并在术后68小时死亡。从血液和筋膜培养物中分离出一株大肠杆菌。DNA微阵列显示存在20个毒力基因。
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