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3
Necrotising fasciitis with Escherichia coli in a newborn infant after abdominal surgery.一名新生儿腹部手术后发生大肠杆菌所致坏死性筋膜炎。
Arch Dis Child Fetal Neonatal Ed. 2013 Sep;98(5):F404. doi: 10.1136/archdischild-2013-303771. Epub 2013 Apr 9.
4
Effect of crowding by Ficolls on OmpA and OmpT refolding and membrane insertion.菲可氏（Ficolls）对 OmpA 和 OmpT 重折叠和膜插入的拥挤效应。
Protein Sci. 2013 Feb;22(2):239-45. doi: 10.1002/pro.2205. Epub 2012 Dec 29.
5
Unusual "flesh-eating" strains of Escherichia coli.不常见的“食人肉”型大肠杆菌。
J Clin Microbiol. 2012 Dec;50(12):4008-11. doi: 10.1128/JCM.02316-12. Epub 2012 Oct 3.
6
Roles of iron acquisition systems in virulence of extraintestinal pathogenic Escherichia coli: salmochelin and aerobactin contribute more to virulence than heme in a chicken infection model.铁获取系统在肠外致病性大肠杆菌毒力中的作用：在鸡感染模型中，沙门菌素和aerobactin 比血红素对毒力的贡献更大。
BMC Microbiol. 2012 Jul 20;12:143. doi: 10.1186/1471-2180-12-143.
7
Necrotizing fasciitis of thigh associated with Escherichia coli bacteremia in a patient on chronic hemodialysis.一名接受慢性血液透析的患者发生大腿坏死性筋膜炎并伴有大肠杆菌菌血症。
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8
The microbiological profile and presence of bloodstream infection influence mortality rates in necrotizing fasciitis.微生物特征和血流感染的存在影响坏死性筋膜炎的死亡率。
Crit Care. 2011 Jun 21;15(3):R152. doi: 10.1186/cc10278.
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Necrotizing fasciitis caused by Staphylococcus aureus: the emergence of methicillin-resistant strains.金黄色葡萄球菌引起的坏死性筋膜炎：耐甲氧西林菌株的出现。
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Unusual "flesh-eating" strain of Escherichia coli.不常见的“食人肉”型大肠杆菌。
J Clin Microbiol. 2010 Oct;48(10):3794-6. doi: 10.1128/JCM.00491-10. Epub 2010 Aug 4.

一例由高毒力大肠杆菌菌株引起的坏死性筋膜炎致死病例。

A Fatal Case of Necrotizing Fasciitis Caused by a Highly Virulent Escherichia coli Strain.

作者信息

Bekal Sadjia, Vincent André, Lin Alex, Harel Josée, Côté Jean-Charles, Tremblay Cécile

机构信息

Laboratoire de Santé Publique du Québec, Sainte-Anne-de-Bellevue, QC, Canada H9X 3R5; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC, Canada H3T 1J4.

Centre Hospitalier Affilié Universitaire, Hôtel-Dieu de Lévis, Lévis, QC, Canada G6V 3Z1.

出版信息

Can J Infect Dis Med Microbiol. 2016;2016:2796412. doi: 10.1155/2016/2796412. Epub 2016 May 31.

DOI:10.1155/2016/2796412
PMID:27366162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4906195/
Abstract

Necrotizing fasciitis is a serious disease characterized by the necrosis of the subcutaneous tissues and fascia. E. coli as the etiologic agent of necrotizing fasciitis is a rare occurrence. A 66-year-old woman underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. She rapidly developed necrotizing fasciitis which led to her death 68 hours following surgery. An E. coli strain was isolated from blood and fascia cultures. DNA microarray revealed the presence of 20 virulence genes.

摘要

坏死性筋膜炎是一种以皮下组织和筋膜坏死为特征的严重疾病。大肠杆菌作为坏死性筋膜炎的病原体较为罕见。一名66岁女性接受了全腹子宫切除术及双侧输卵管卵巢切除术。术后她迅速发展为坏死性筋膜炎，并在术后68小时死亡。从血液和筋膜培养物中分离出一株大肠杆菌。DNA微阵列显示存在20个毒力基因。