• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

表现为脑肿瘤的恶性转移性类癌。

Malignant metastatic carcinoid presenting as brain tumor.

作者信息

Sundar I Vijay, Jain S K, Kurmi Dhrubajyoti, Sharma Rakesh, Chopra Sanjeev, Singhvi Shashi

机构信息

Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India.

Department of Pathology, SMS Medical College, Jaipur, Rajasthan, India.

出版信息

Asian J Neurosurg. 2016 Jul-Sep;11(3):314. doi: 10.4103/1793-5482.145319.

DOI:10.4103/1793-5482.145319
PMID:27366273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4849315/
Abstract

Carcinoid tumors are rarely known to metastasise to the brain. It is even more rare for such patients to present with symptoms related to metastases as the initial and only symptom. We present a case of a 60-year-old man who presented with hemiparesis and imaging features suggestive of brain tumor. He underwent surgery and the histopathology revealed metastatic malignant lesion of neuroendocrine origin. A subsequent work up for the primary was negative. Patient was treated with adjuvant radiotherapy. We present this case to highlight the pathophysiological features, workup and treatment options of this rare disease and discuss the methods of differentiating it from more common brain tumors.

摘要

类癌肿瘤很少发生脑转移。此类患者以转移相关症状作为首发且唯一症状的情况更为罕见。我们报告一例60岁男性患者,其表现为偏瘫及提示脑肿瘤的影像学特征。他接受了手术,组织病理学检查显示为神经内分泌起源的转移性恶性病变。随后对原发灶的检查结果为阴性。患者接受了辅助放疗。我们呈现此病例以突出这种罕见疾病的病理生理特征、检查及治疗选择,并讨论将其与更常见脑肿瘤相鉴别的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/8649f454eb94/AJNS-11-314-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/13357c194b9f/AJNS-11-314-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/324a6cdac642/AJNS-11-314-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/4f56524d45f4/AJNS-11-314-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/8649f454eb94/AJNS-11-314-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/13357c194b9f/AJNS-11-314-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/324a6cdac642/AJNS-11-314-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/4f56524d45f4/AJNS-11-314-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4b/4849315/8649f454eb94/AJNS-11-314-g004.jpg

相似文献

1
Malignant metastatic carcinoid presenting as brain tumor.表现为脑肿瘤的恶性转移性类癌。
Asian J Neurosurg. 2016 Jul-Sep;11(3):314. doi: 10.4103/1793-5482.145319.
2
Atypical ovarian carcinoid tumor with widespread skeletal metastases: a case report of multiple endocrine neoplasia type 1 in a young woman.伴有广泛骨骼转移的非典型卵巢类癌瘤:一例年轻女性 1 型多发性内分泌肿瘤病例报告。
BMC Cancer. 2019 Nov 14;19(1):1107. doi: 10.1186/s12885-019-6332-7.
3
Infection with multidrug-resistant Campylobacter coli mimicking recurrence of carcinoid syndrome: a case report of a neuroendocrine tumor patient with repeated diarrhea.多重耐药空肠弯曲菌感染酷似类癌综合征复发:一例神经内分泌肿瘤患者反复腹泻的病例报告
BMC Infect Dis. 2016 Aug 12;16:409. doi: 10.1186/s12879-016-1743-4.
4
Incidental metastatic mediastinal atypical carcinoid in a patient with parathyroid adenoma: a case report.甲状旁腺腺瘤患者伴发纵隔转移性非典型类癌:一例报告
J Med Case Rep. 2017 Mar 26;11(1):81. doi: 10.1186/s13256-017-1234-2.
5
Hepatic surgery for metastases from neuroendocrine tumors.神经内分泌肿瘤肝转移的肝手术治疗
Surg Oncol Clin N Am. 2003 Jan;12(1):231-42. doi: 10.1016/s1055-3207(02)00076-5.
6
Carcinoid tumor presenting as a primary mesenteric mass: a case report and review of the literature.以原发性肠系膜肿块为表现的类癌肿瘤:一例病例报告及文献复习
Hawaii Med J. 2009 Jul;68(6):137-9.
7
Metastatic carcinoid presenting as a breast lesion.转移性类癌表现为乳腺病变。
Curr Oncol. 2010 Nov;17(6):73-7. doi: 10.3747/co.v17i6.669.
8
Thyroid metastases from typical carcinoid of the lung differentiating between medullary thyroid carcinoma and neuroendocrine tumor metastasis to the thyroid.肺典型类癌的甲状腺转移:鉴别甲状腺髓样癌与神经内分泌肿瘤转移至甲状腺。
Thyroid. 2009 May;19(5):521-6. doi: 10.1089/thy.2008.0424.
9
Metastatic laryngeal large cell neuroendocrine carcinoma: A rare case of presentation and extreme tumor burden.转移性喉大细胞神经内分泌癌:一例罕见的临床表现及极高肿瘤负荷病例。
J Cutan Pathol. 2018 Mar;45(3):229-233. doi: 10.1111/cup.13090. Epub 2017 Dec 28.
10
Primary carcinoid of the testis with metastases. Case report and review of the literature.
J BUON. 2002 Apr-Jun;7(2):153-6.

引用本文的文献

1
Brain Metastasis as the Initial Presentation of Carcinoid Tumor: Case Report and Literature Review.类癌肿瘤以脑转移为首发表现:病例报告及文献综述
J Investig Med High Impact Case Rep. 2025 Jan-Dec;13:23247096251339308. doi: 10.1177/23247096251339308. Epub 2025 May 9.
2
Case report: Efficacy of lutetium-177 oxodotreotide for neuroendocrine tumor with central nervous system metastases.病例报告:镥-177奥曲肽治疗中枢神经系统转移神经内分泌肿瘤的疗效
Front Nucl Med. 2023 Feb 23;3:1074948. doi: 10.3389/fnume.2023.1074948. eCollection 2023.
3
Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis.

本文引用的文献

1
ENETS consensus guidelines for the management of brain, cardiac and ovarian metastases from neuroendocrine tumors.神经内分泌肿瘤脑、心脏和卵巢转移管理的ENETS共识指南。
Neuroendocrinology. 2010;91(4):326-32. doi: 10.1159/000287277. Epub 2010 May 6.
2
Metastatic carcinoid tumors: a clinical review.转移性类癌肿瘤:临床综述
Oncologist. 2005 Feb;10(2):123-31. doi: 10.1634/theoncologist.10-2-123.
3
Carcinoid metastasis to the brain.类癌转移至脑。
新型胰腺神经内分泌肿瘤转移发光小鼠模型的建立与比较。
Sci Rep. 2021 May 13;11(1):10252. doi: 10.1038/s41598-021-89866-1.
4
Neuroendocrine breast carcinoma metastasis to the brain.神经内分泌性乳腺癌脑转移
BMJ Case Rep. 2019 Mar 7;12(3):e228846. doi: 10.1136/bcr-2018-228846.
Cancer. 2004 Dec 1;101(11):2605-13. doi: 10.1002/cncr.20659.
4
Single brain metastases of carcinoid tumors.类癌肿瘤的单发性脑转移瘤
J Neurooncol. 2004 Feb;66(3):327-32. doi: 10.1023/b:neon.0000014517.56866.bc.
5
Pulmonary carcinoid found in a patient who presented with initial symptoms of brain metastasis: report of a case.在一名以脑转移初始症状就诊的患者中发现肺类癌:病例报告
Surg Today. 2001;31(6):510-2. doi: 10.1007/s005950170111.
6
Intracranial carcinoid without evidence of extracranial disease.颅内类癌,无颅外疾病证据。
Neuropathol Appl Neurobiol. 2000 Jun;26(3):298-300. doi: 10.1046/j.1365-2990.2000.00257.x.
7
Multicystic metastatic carcinoid to brain: case report.脑内多囊性转移性类癌:病例报告
J Neurooncol. 1993 Jul;17(1):15-20. doi: 10.1007/BF01054269.
8
Radiation therapy in the management of patients with malignant carcinoid tumors.
Cancer. 1995 Mar 15;75(6):1386-90. doi: 10.1002/1097-0142(19950315)75:6<1386::aid-cncr2820750622>3.0.co;2-u.
9
Neurologic complications of carcinoid.类癌的神经并发症
Neurology. 1986 Jun;36(6):745-9. doi: 10.1212/wnl.36.6.745.
10
Carcinoid tumor presenting as central nervous system symptoms. Case report and review of the literature.以中枢神经系统症状为表现的类癌肿瘤。病例报告及文献综述。
Am J Clin Oncol. 1990 Jun;13(3):251-5. doi: 10.1097/00000421-199006000-00015.