Erdoğan Mehmet Ali, Uçar Muharrem, Özkan Ahmet Selim, Özgül Ülkü, Durmuş Mahmut
Department of Anaesthesiology and Reanimation, İnönü University School of Medicine, Turgut Özal Medical Center, Malatya, Turkey.
Turk J Anaesthesiol Reanim. 2016 Feb;44(1):47-9. doi: 10.5152/TJAR.2016.25993. Epub 2016 Feb 1.
Phaeochromocytoma is a catecholamine-secreting vascular tumour that is derived from chromaffin cell. Lethal cardiovascular complications, such as serious hypertension, myocardial infarction and aortic dissection, may occur because of uncontrolled catecholamine release. Each stage of anaesthesia management has vital importance because of this destructive catecholamine secretion that may occur during induction, perioperative stage and surgical manipulation. In this study, we report regarding the preoperative preparation and severe, persistent hypertension attack management with a combination of α-adrenergic blockade, β-adrenergic blockade, sodium nitroprusside and remifentanil in a patient who underwent laparoscopic surgery for phaeochromocytoma.
嗜铬细胞瘤是一种分泌儿茶酚胺的血管肿瘤，起源于嗜铬细胞。由于儿茶酚胺释放不受控制，可能会发生致命的心血管并发症，如严重高血压、心肌梗死和主动脉夹层。由于在诱导期、围手术期和手术操作过程中可能会出现这种具有破坏性的儿茶酚胺分泌，麻醉管理的每个阶段都至关重要。在本研究中，我们报告了一名接受腹腔镜嗜铬细胞瘤手术患者的术前准备以及联合使用α-肾上腺素能阻滞剂、β-肾上腺素能阻滞剂、硝普钠和瑞芬太尼治疗严重持续性高血压发作的情况。
