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来自两个社会经济阶层的印度小于胎龄儿的生长状况。

Growth status of small for gestational age Indian children from two socioeconomic strata.

作者信息

Khadilkar Vaman V, Mandlik Rubina M, Palande Sonal A, Pandit Deepa S, Chawla Meghna, Nadar Ruchi, Chiplonkar Shashi A, Kadam Sandeep S, Khadilkar Anuradha A

机构信息

Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India.

Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.

出版信息

Indian J Endocrinol Metab. 2016 Jul-Aug;20(4):531-5. doi: 10.4103/2230-8210.183473.

Abstract

AIMS

To assess growth and factors associated with growth in children born small for gestational age (SGA) from two socioeconomic strata in comparison to age- and sex-matched healthy controls.

METHODS

Retrospective study conducted at two hospitals in Pune, 0.5-5 years, 618 children: 189-SGA from upper socioeconomic strata (USS), 217-SGA from lower socioeconomic strata (LSS), and 212 appropriate for gestational age healthy controls were randomly selected. Birth and maternal history, socioeconomic status, length/height, and weight of children were recorded. Anthropometric data were converted to Z scores (height for age Z-score [HAZ], weight for age Z-score [WAZ]) using WHO AnthroPlus software.

RESULTS

The HAZ and WAZ of the SGA group were significantly lower as compared to the controls and that of the LSS SGAs were lower than USS SGAs (P < 0.05). Thirty two percent children were stunted (HAZ <-2.0) in USS and 49% in LSS (P < 0.05). Twenty nine percent children in the USS SGA group were stunted at 2 years and 17% at 5 years. In the LSS SGA group, 54% children were stunted at 2 years and 46% at 5 years. Generalized linear model revealed normal vaginal delivery (β = 0.625) and mother's age (β =0.072) were positively associated and high SES (β = -0.830), absence of major illness (β = -1.01), higher birth weight (β = -1.34) were negatively associated for risk of stunting (P < 0.05).

CONCLUSION

Children born SGA showed poor growth as compared to controls. Special attention to growth is necessary in children from LSS, very low birth weight babies, and those with major illnesses during early years of life.

摘要

目的

评估来自两个社会经济阶层的小于胎龄儿(SGA)儿童的生长情况以及与生长相关的因素,并与年龄和性别匹配的健康对照进行比较。

方法

在普纳的两家医院进行回顾性研究,研究对象为0.5至5岁的618名儿童:随机选取189名来自社会经济上层(USS)的SGA儿童、217名来自社会经济下层(LSS)的SGA儿童以及212名适于胎龄的健康对照。记录儿童的出生和母亲病史、社会经济状况、身长/身高和体重。使用WHO AnthroPlus软件将人体测量数据转换为Z评分(年龄别身高Z评分[HAZ]、年龄别体重Z评分[WAZ])。

结果

与对照组相比,SGA组的HAZ和WAZ显著更低,且LSS SGA儿童的HAZ和WAZ低于USS SGA儿童(P<0.05)。USS组32%的儿童发育迟缓(HAZ<-2.0),LSS组为49%(P<0.05)。USS SGA组中,29%的儿童在2岁时发育迟缓,5岁时为17%。在LSS SGA组中,54%的儿童在2岁时发育迟缓,5岁时为46%。广义线性模型显示,正常阴道分娩(β=0.625)和母亲年龄(β=0.072)与发育迟缓风险呈正相关,而高社会经济地位(β=-0.830)、无重大疾病(β=-1.01)、较高出生体重(β=-1.34)与发育迟缓风险呈负相关(P<0.05)。

结论

与对照组相比,SGA出生的儿童生长较差。对于来自LSS的儿童、极低出生体重儿以及生命早期患有重大疾病的儿童,有必要特别关注其生长情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84d0/4911844/6c3e2cdf8fcf/IJEM-20-531-g004.jpg

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