Łagocka Ryta, Jakubowska Katarzyna, Chlubek Dariusz, Buczkowska-Radlińska Jadwiga
Department of Conservative Dentistry, Pomeranian Medical University, Powstańców Wlkp. Avenue 72, 70-111 Szczecin, Poland.
Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Powstańców Wlkp. Avenue 72, 70-111 Szczecin, Poland.
Biomed Res Int. 2016;2016:3481723. doi: 10.1155/2016/3481723. Epub 2016 Jun 6.
Objective. This study aimed to evaluate triethylene glycol dimethacrylate (TEGDMA) elution from SDR bulk-fill composite. Methods. Three groups of samples were prepared, including samples polymerized in a 4 mm layer for 20 s, in a 4 mm layer for 40 s, and in a 2 mm layer for 20 s. Elution of TEGDMA into 100% ethanol, a 75% ethanol/water solution, and distilled water was studied. The TEGDMA concentration was measured using HPLC. Results. The TEGDMA concentration decreased in the following order: 100% ethanol > 75% ethanol > distilled water. Doubling the energy delivered to the 4 mm thick sample caused decrease (p < 0.05) in TEGDMA elution to distilled water. In ethanol solutions, the energy increase had no influence on TEGDMA elution. Decreasing the sample thickness resulted in decrease (p < 0.05) in TEGDMA elution for all the solutions. Conclusions. The concentration of eluted TEGDMA and the elution time were both strongly affected by the hydrophobicity of the solvent. Doubling the energy delivered to the 4 mm thick sample did not decrease the elution of TEGDMA but did decrease the amount of the monomer available to less aggressive solvents. Elution of TEGDMA was also correlated with the exposed sample surface area. Clinical Relevance. Decreasing the SDR layer thickness decreases TEGDMA elution.
目的。本研究旨在评估自酸蚀粘接（SDR）大块充填复合树脂中三乙二醇二甲基丙烯酸酯（TEGDMA）的溶出情况。方法。制备三组样品，包括在4毫米厚度层中聚合20秒的样品、在4毫米厚度层中聚合40秒的样品以及在2毫米厚度层中聚合20秒的样品。研究了TEGDMA在100%乙醇溶液、75%乙醇/水溶液和蒸馏水中的溶出情况。使用高效液相色谱法（HPLC）测量TEGDMA浓度。结果。TEGDMA浓度按以下顺序降低：100%乙醇＞75%乙醇＞蒸馏水。将输送至4毫米厚样品的能量加倍会导致TEGDMA在蒸馏水中的溶出量减少（p＜0.05）。在乙醇溶液中，能量增加对TEGDMA溶出没有影响。减小样品厚度会导致所有溶液中TEGDMA的溶出量减少（p＜0.05）。结论。溶出的TEGDMA浓度和溶出时间均受溶剂疏水性的强烈影响。将输送至4毫米厚样品的能量加倍不会降低TEGDMA的溶出量，但会减少可用于侵蚀性较小溶剂的单体量。TEGDMA的溶出还与暴露的样品表面积相关。临床意义。减小SDR层厚度会降低TEGDMA的溶出。
