Yang Fang, Mipam TserangDonko, Sun Lei, Yu Shumin, Cai Xin
College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, Sichuan, China.
College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, Sichuan, China.
Data Brief. 2016 Jun 3;8:420-5. doi: 10.1016/j.dib.2016.05.071. eCollection 2016 Sep.
Cattleyak are hybrid between cattle and yak, which exhibit equivalent adaptability on the Qinghai-Tibetan Plateau as yak and much higher capability in economic traits. However, the F1 males of cattleyak are infertile due to spermatogenic arrest and this greatly restricts the effective utilization of this hybrid. In this data article, differentially expressed proteins (DEPs) were identified from testis proteome of cattleyak and yak using high-performance liquid chromatography-electrospray tandem mass spectrometry (LC-ESI-MS/MS). All the DEPs were subjected to functional classification by Gene Ontology (GO) analysis and gene-pathway annotation by Kyoto Encyclopedia of Genes and Genomes (KEGG). The comparative testis proteome dataset here can shed new light on the molecular characteristics of male infertility of cattleyak on proteome level, "Comparative iTRAQ proteomics revealed proteins associated with spermatogenic arrest of cattleyak" [1].
犏牛是牛和牦牛的杂交种,在青藏高原上表现出与牦牛相当的适应性,且在经济性状方面能力更强。然而,犏牛的F1雄性由于生精停滞而不育,这极大地限制了这种杂交种的有效利用。在这篇数据文章中,使用高效液相色谱-电喷雾串联质谱(LC-ESI-MS/MS)从犏牛和牦牛的睾丸蛋白质组中鉴定出差异表达蛋白(DEP)。所有DEP通过基因本体论(GO)分析进行功能分类,并通过京都基因与基因组百科全书(KEGG)进行基因-通路注释。此处的比较睾丸蛋白质组数据集能够在蛋白质组水平上为犏牛雄性不育的分子特征提供新的见解,“比较iTRAQ蛋白质组学揭示了与犏牛生精停滞相关的蛋白质”[1]。