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无均整器射束的TRS - 398操作规范与TG - 51剂量测定协议的比较。

Comparison between the TRS-398 code of practice and the TG-51 dosimetry protocol for flattening filter free beams.

作者信息

Lye J E, Butler D J, Oliver C P, Alves A, Lehmann J, Gibbons F P, Williams I M

机构信息

Australian Clinical Dosimetry Service (ACDS), Yallambie, Australia. RMIT University, Melbourne, Australia.

出版信息

Phys Med Biol. 2016 Jul 21;61(14):N362-72. doi: 10.1088/0031-9155/61/14/N362. Epub 2016 Jul 1.

DOI:10.1088/0031-9155/61/14/N362
PMID:27366933
Abstract

Dosimetry protocols for external beam radiotherapy currently in use, such as the IAEA TRS-398 and AAPM TG-51, were written for conventional linear accelerators. In these accelerators, a flattening filter is used to produce a beam which is uniform at water depths where the ionization chamber is used to measure the absorbed dose. Recently, clinical linacs have been implemented without the flattening filter, and published theoretical analysis suggested that with these beams a dosimetric error of order 0.6% could be expected for IAEA TRS-398, because the TPR20,10 beam quality index does not accurately predict the stopping power ratio (water to air) for the softer flattening-filter-free (FFF) beam spectra. We measured doses on eleven FFF linacs at 6 MV and 10 MV using both dosimetry protocols and found average differences of 0.2% or less. The expected shift due to stopping powers was not observed. We present Monte Carlo k Q calculations which show a much smaller difference between FFF and flattened beams than originally predicted. These results are explained by the inclusion of the added backscatter plates and build-up filters used in modern clinical FFF linacs, compared to a Monte Carlo model of an FFF linac in which the flattening filter is removed and no additional build-up or backscatter plate is added.

摘要

目前正在使用的外照射放疗剂量测定协议,如国际原子能机构的TRS - 398和美国医学物理师协会的TG - 51,是为传统直线加速器编写的。在这些加速器中,使用了一个均整滤过器来产生一束在电离室用于测量吸收剂量的水深处均匀的射束。最近,临床直线加速器已经在不使用均整滤过器的情况下运行,并且已发表的理论分析表明,对于国际原子能机构的TRS - 398,使用这些射束时可能预期有0.6%量级的剂量测定误差,因为TPR20,10射束质量指数不能准确预测较软的无均整滤过器(FFF)射束谱的阻止本领比(水对空气)。我们使用这两种剂量测定协议在11台6 MV和10 MV的FFF直线加速器上测量了剂量,发现平均差异在0.2%或更小。未观察到因阻止本领导致的预期偏移。我们给出了蒙特卡罗kQ计算结果,其显示FFF射束和平坦射束之间的差异比最初预测的要小得多。与一个去除了均整滤过器且未添加额外的建成或散射板的FFF直线加速器蒙特卡罗模型相比,现代临床FFF直线加速器中使用的附加散射板和建成滤过器的纳入解释了这些结果。

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