Gotzaridis Stratos, Liazos Efstathios, Petrou Petros, Georgalas Ilias
a Athens Retina Institute , Athens , Greece.
b First Department of Ophthalmology, G. Genimatas University Hospital , Athens , Greece.
Semin Ophthalmol. 2017;32(5):597-601. doi: 10.3109/08820538.2015.1132333. Epub 2016 Jul 1.
A retrospective consecutive case series to evaluate the safety and efficacy of 25 gauge pars plana vitrectomy, ILM peeling, 20% SF gas tamponade and strict posturing for the treatment of idiopathic full-thickness macular holes.
We report the results of 106 consecutive eyes that underwent standard 25-gauge pars plana vitrectomy, brilliant peel-assisted internal limiting membrane peel, fluid:gas exchange with 20% SF and strict posturing for one week. All patients were followed up at one week, one month, three months, and nine months postoperatively. Biomicroscopy at day 1 and biomicroscopy and OCT at week 1, months 1, 3, and 9 were used to assess macular hole status postoperatively. Pre- and postoperative logMAR visual acuity was compared.
The macular hole was closed in 102/106 eyes postoperatively (96.2%). Four eyes showed unclosed macular holes and underwent additional SF intravitreal injection and strict posturing for 10 days. All macular holes were eventually closed without the need of a second surgical procedure. Mean visual acuity improved from 0.63 logMAR preoperatively to 0.39 logMAR postoperatively. One case of retinal toxicity was reported due to accidental intravitreal injection of antibiotic.
25-gauge vitrectomy, ILM peel, and short-acting gas tamponade are highly effective for the treatment of macular holes. Additional intravitreal gas injection followed by strict posturing seems to be a simple and effective treatment for unclosed holes.
一项回顾性连续病例系列研究,以评估25G经睫状体平坦部玻璃体切除术、内界膜剥除术、20%全氟丙烷气体填塞及严格体位疗法治疗特发性全层黄斑裂孔的安全性和有效性。
我们报告了106例连续眼的结果,这些眼均接受了标准的25G经睫状体平坦部玻璃体切除术、亮剥辅助内界膜剥除术、20%全氟丙烷气体液体-气体交换及一周的严格体位疗法。所有患者在术后1周、1个月、3个月和9个月进行随访。术后第1天进行生物显微镜检查,术后1周、1个月、3个月和9个月进行生物显微镜检查和光学相干断层扫描(OCT),以评估黄斑裂孔状态。比较术前和术后的对数最小分辨角视力(logMAR)。
术后102/106眼(96.2%)黄斑裂孔闭合。4眼黄斑裂孔未闭合,接受了额外的玻璃体内全氟丙烷注射及10天的严格体位疗法。所有黄斑裂孔最终均闭合,无需二次手术。平均视力从术前的0.63 logMAR提高到术后的0.39 logMAR。报告了1例因意外玻璃体内注射抗生素导致的视网膜毒性病例。
25G玻璃体切除术、内界膜剥除术及短效气体填塞对黄斑裂孔的治疗非常有效。额外的玻璃体内气体注射并严格体位疗法似乎是治疗未闭合黄斑裂孔的一种简单有效的方法。