Rubinstein Adrian, Ang Alan, Patel Chetan Kantibhai
Oxford Eye Hospital, Radcliffe Infirmary, Oxford, UK.
Clin Exp Ophthalmol. 2007 Jul;35(5):458-61. doi: 10.1111/j.1442-9071.2007.01532.x.
To determine the success of vitrectomy with ILM peeling and C(3)F(8) tamponade for macular holes without the need for postoperative face-down posturing.
Twenty-four eyes of 24 consecutive patients undergoing pars plana vitrectomy with indocyanine green-assisted ILM peeling and C(3)F(8) tamponade without prone posturing were included in the study. All patients had follow up on 1 day, 2 weeks and 3 months postoperatively. Biomicroscopy and optical coherence tomography were used to assess macular hole closure at 3 months postoperatively. Snellen visual acuity was compared pre- and postoperatively.
Of the 24 eyes recruited, two (8%) had stage II, 17 (71%) had stage III and five (21%) had stage IV macular holes. Nineteen (79%) eyes were phakic and five (21%) eyes were pseudophakic at the time of surgery. The macular holes had been present for an average of 7.5 months (range 3-18 months). At 3-month follow up, 22/24 (91.6%) holes were closed. Both of the two holes that failed to close were stage IV macular holes. Preoperative visual acuity ranged from 6/18 to 6/60 (mean 6/36). Postoperative visual acuity ranged from 6/9 to 6/60 (mean 6/18). Eighteen eyes had improvement of visual acuity of at least one line on the Snellen chart, six eyes had no improvement. No eyes had worse vision postoperatively.
Macular hole surgery without face-down posturing provides anatomical and functional results comparable to those with prone posturing. Combined phacovitrectomy is not essential to avoid prone posturing.
确定在无需术后俯卧位姿势的情况下,行内界膜剥除联合C(3)F(8)填充的玻璃体切除术治疗黄斑裂孔的成功率。
本研究纳入24例连续患者的24只眼,这些患者均接受了经平坦部玻璃体切除术,术中使用吲哚菁绿辅助内界膜剥除并采用C(3)F(8)填充,术后无需俯卧位姿势。所有患者在术后1天、2周和3个月进行随访。术后3个月时,使用生物显微镜和光学相干断层扫描评估黄斑裂孔闭合情况。比较术前和术后的Snellen视力。
在纳入的24只眼中,2只(8%)为Ⅱ期黄斑裂孔,17只(71%)为Ⅲ期黄斑裂孔, 5只(21%)为Ⅳ期黄斑裂孔。手术时,19只(79%)眼为有晶状体眼,5只(21%)眼为人工晶状体眼。黄斑裂孔平均存在时间为7.5个月(范围3 - 18个月)。在3个月随访时,22/24(91.6%)个裂孔闭合。未闭合的2个裂孔均为Ⅳ期黄斑裂孔。术前视力范围为6/18至6/60(平均6/36);术后视力范围为6/9至6/60(平均6/18)。18只眼Snellen视力表上的视力至少提高了一行,6只眼无改善。术后无眼视力变差。
无需俯卧位姿势的黄斑裂孔手术在解剖和功能方面的结果与采用俯卧位姿势的手术相当。联合晶状体玻璃体切除术并非避免俯卧位姿势所必需。