Pan Hua, Jian Fan, Lin Jinxi, Chen Na, Zhang Zaiqiang, Wang Yongjun, Cui Liying, Kimura Jun
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.
Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China.
Muscle Nerve. 2016 Dec;54(6):1093-1096. doi: 10.1002/mus.25236. Epub 2016 Sep 26.
We sought to determine which muscles to choose for better assessment of the craniobulbar region in establishing the diagnosis of amyotrophic lateral sclerosis (ALS).
We studied the frontalis muscle in 83 controls and compared it with the tongue, sternocleidomastoid (SCM), and trapezius muscles in 105 definite or probable ALS patients (54 bulbar, 51 nonbulbar).
More patients achieved complete relaxation of the frontalis muscle than the tongue or SCM. Motor unit potentials were of longer duration and higher amplitude in ALS patients than in controls (P < 0.05). The frontalis had the same frequency of spontaneous potentials as the tongue, SCM, and trapezius muscles in bulbar ALS patients, but fewer than in the trapezius in nonbulbar patients.
Examining the frontalis provides useful information in establishing the diagnosis of ALS by identifying clinically evident or subclinical abnormalities in the craniobulbar region. Muscle Nerve 54: 1093-1096, 2016.
我们试图确定在肌萎缩侧索硬化症（ALS）诊断中，选择哪些肌肉能更好地评估颅神经支配区。
我们研究了83名对照者的额肌，并将其与105名明确或可能患有ALS的患者（54名延髓型，51名非延髓型）的舌肌、胸锁乳突肌（SCM）和斜方肌进行比较。
与舌肌或胸锁乳突肌相比，更多患者的额肌能实现完全放松。ALS患者的运动单位电位持续时间更长、波幅更高，与对照者相比差异有统计学意义（P < 0.05）。在延髓型ALS患者中，额肌的自发电位频率与舌肌、胸锁乳突肌和斜方肌相同，但在非延髓型患者中，额肌的自发电位频率低于斜方肌。
通过识别颅神经支配区临床上明显或亚临床的异常情况，检查额肌可为ALS的诊断提供有用信息。《肌肉与神经》54: 1093 - 1096, 2016年。
