一例遗传性黄嘌呤尿症新病例：对运动的反应
A new case with hereditary xanthinuria: response to exercise.
作者信息
Landaas S, Borch K, Aagaard E
机构信息
Central Laboratory, Ullevaal University Hospital, Oslo, Norway.
出版信息
Clin Chim Acta. 1989 May 15;181(2):119-24. doi: 10.1016/0009-8981(89)90178-2.
The concentration of purines in plasma and urine from a 37-yr-old healthy man with a very low plasma urate concentration was measured by HPLC. A persistent increase in xanthine and a slight elevation of hypoxanthine was found. The metabolic response to intensive treadmill running and long distance running was investigated. The hypoxanthine concentration increased to about the same level as in healthy controls, but the elimination from plasma was considerably slower. The high xanthine level was practically unchanged by exercise.
采用高效液相色谱法（HPLC）测定了一名37岁血浆尿酸盐浓度极低的健康男性的血浆和尿液中的嘌呤浓度。发现黄嘌呤持续增加，次黄嘌呤略有升高。研究了高强度跑步机跑步和长跑的代谢反应。次黄嘌呤浓度升高至与健康对照组大致相同的水平，但从血浆中的清除速度明显较慢。运动对高黄嘌呤水平几乎没有影响。
Zotero 插件