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两名低补体血症性膜增生性肾小球肾炎患者血清中的C3肾炎因子和C4肾炎因子

C3 nephritic factor and C4 nephritic factor in the serum of two patients with hypocomplementaemic membranoproliferative glomerulonephritis.

作者信息

Tanuma Y, Ohi H, Watanabe S, Seki M, Hatano M

机构信息

Second Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.

出版信息

Clin Exp Immunol. 1989 Apr;76(1):82-5.

Abstract

Both C3 nephritic factor (C3NeF) and C4 nephritic factor (C4NeF) were found in the serum of two patients with hypocomplementaemic membranoproliferative glomerulonephritis type 1 (H-MPGN type 1). Both stabilizing activities were associated with the IgG fraction. The serum levels of C3 and C5 were quite low, whereas the levels of early components and control proteins were in the normal range.

摘要

在两名1型低补体血症性膜增生性肾小球肾炎(H-MPGN 1型)患者的血清中发现了C3肾炎因子(C3NeF)和C4肾炎因子(C4NeF)。两种稳定活性均与IgG组分相关。C3和C5的血清水平相当低,而早期补体成分和对照蛋白的水平在正常范围内。

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