Sesso R, Draibe S, Castelo A, Sato I, Leme I, Barbosa D, Ramos O
Division of Nephrology, Escola Paulista de Medicina, São Paulo, Brazil.
Clin Nephrol. 1989 May;31(5):264-8.
We conducted a 15-month prospective study to investigate the skin carriage of Staphylococcus aureus and the development of peritonitis in 43 patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Sixteen of 43 patients (37%) were chronic carriers of S. aureus in the anterior nares and/or in the exit-site of the catheter; 12 patients (28%) were intermittent carriers, and 15 (35%) were noncarriers. Fifty episodes of peritonitis occurred during a total of 422 patient-months of observation. S. aureus was responsible for 16 episodes of peritonitis diagnosed in 15 patients. All episodes of S. aureus peritonitis occurred in chronic and intermittent carriers. Phage typing was performed on isolates from 8 patients with S. aureus peritonitis, and they were found to have the same phage type as that previously carried in the skin. We conclude that CAPD patients who are chronic or intermittent carriers of S. aureus are at higher risk of development of peritonitis than noncarriers.
我们进行了一项为期15个月的前瞻性研究，以调查43例持续性非卧床腹膜透析（CAPD）患者金黄色葡萄球菌的皮肤携带情况及腹膜炎的发生情况。43例患者中有16例（37%）是金黄色葡萄球菌在前鼻孔和/或导管出口部位的慢性携带者；12例患者（28%）是间歇性携带者，15例（35%）是非携带者。在总共422个患者月的观察期间发生了50次腹膜炎发作。金黄色葡萄球菌导致了15例患者诊断出的16次腹膜炎发作。所有金黄色葡萄球菌腹膜炎发作均发生在慢性和间歇性携带者中。对8例金黄色葡萄球菌腹膜炎患者的分离株进行了噬菌体分型，发现它们与先前皮肤携带的噬菌体类型相同。我们得出结论，金黄色葡萄球菌的慢性或间歇性携带者的CAPD患者发生腹膜炎的风险高于非携带者。
