Piirilä P, Sovijärvi A R
Department of Pulmonary Medicine, Helsinki University Central Hospital, Finland.
Chest. 1989 Jul;96(1):46-53. doi: 10.1378/chest.96.1.46.
The aim of this study was to determine whether the flow dynamics and sound spectra of spontaneous cough show characteristic differences in asthma, acute and chronic bronchitis, TBCS and FPD. During the cough, the air flow from the mouth and the sound from the sternal manubrium were simultaneously recorded. The cough sounds were analyzed spectrographically. Peak expiratory flow during cough was significantly lower in asthma than in TBCS, acute bronchitis or FPD. Duration of the first cough sound was longer in asthma than in FPD, TBCS or chronic bronchitis. The number of additional cough sounds was smaller in asthma than in the other conditions. The highest frequency components of cough sound were lower in asthma than in chronic bronchitis or TBCS. The results indicate that pulmonary diseases differ with respect to acoustic and dynamic characteristics of spontaneous cough. This finding may prove useful in the diagnosis of cough.
本研究的目的是确定自发性咳嗽的气流动力学和声谱在哮喘、急慢性支气管炎、支气管内膜结核（TBCS）和肺功能障碍（FPD）中是否表现出特征性差异。咳嗽期间，同时记录口腔气流和胸骨柄处的声音。对咳嗽声音进行频谱分析。哮喘患者咳嗽时的呼气峰值流速显著低于支气管内膜结核、急性支气管炎或肺功能障碍患者。哮喘患者首次咳嗽声音的持续时间比肺功能障碍、支气管内膜结核或慢性支气管炎患者长。哮喘患者额外咳嗽声音的数量比其他情况少。哮喘患者咳嗽声音的最高频率成分低于慢性支气管炎或支气管内膜结核患者。结果表明，不同肺部疾病在自发性咳嗽的声学和动力学特征方面存在差异。这一发现可能对咳嗽的诊断有用。
