Clinica Goldman, Porto Alegre/RS, Brazil.
Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
J Biol Regul Homeost Agents. 2016 Apr-Jun;30(2 Suppl 2):53-8.
Congenital melanocytic nevi can be stigmatising for the patient. Larger nevi bear an increased risk for melanoma development. Large congenital melanocytic nevi may be a symptom of neurocutaneous melanosis. We report on a 5-year-old boy with an extensive hair-bearing facial congenital melanocytic nevus, covering forehead, glabella and temple region associated with unilateral brow and blepharoptosis. The lesion was excised en bloc. The resulting defect had been closed by full thickness skin graft. Healing was unremarkable and long-term follow-up over 13 years demonstrated a satisfying esthetic and functional outcome. There was no evidence of melanoma development. Surgery is an option for disfiguring larger congenital melanocytic nevi as long as esthetics and function can be preserved. Long-term follow-up is recommended due to the increased risk of melanoma.
先天性黑素细胞痣可能会给患者带来耻辱。较大的痣发生黑色素瘤的风险增加。大型先天性黑素细胞痣可能是神经皮肤黑色素沉着症的症状。我们报告了一例 5 岁男孩，其面部广泛有毛发的先天性黑素细胞痣，覆盖前额、眉间和太阳穴区域，伴有单侧眉毛和上睑下垂。病变整块切除。通过全厚皮片移植闭合了由此产生的缺陷。愈合良好，随访 13 年以上，结果满意，美容和功能均得到保留。没有黑色素瘤发展的证据。对于较大的先天性黑素细胞痣，如果可以保持美观和功能，手术是一种选择。由于黑色素瘤的风险增加，建议进行长期随访。
