Varazashvili P N
Fiziol Zh (1978). 1989 May-Jun;35(3):3-7.
The 6-hour-long continuous electric stimulation of the cat orbital cortex in chronic experiments induced an increased frequency of the spindle-like activity, on the one hand, and the prolongation of slow and paradoxical sleep phases on the average by 25-30% and 3-5%, respectively, at the expense of the reduction of wakefulness and drowsiness periods by 20-25% and 10-15%, respectively, on the other hand. A supposition is advanced that the inhibition of wakefulness and prolongation of the sleep are due to the enhancement of the facilitating impulsation from the orbital cortex to the somnogenic system of the brain. At the same time, the wakefulness system of the brain is most probably inhibited additionally, promoting facilitation of the sleep development.
在慢性实验中,对猫的眶皮质进行长达6小时的连续电刺激,一方面会导致纺锤样活动频率增加,另一方面会使慢波睡眠和异相睡眠阶段平均分别延长25% - 30%和3% - 5%,代价是清醒期和困倦期分别减少20% - 25%和10% - 15%。有人提出一种假设,即清醒的抑制和睡眠的延长是由于从眶皮质到脑内促睡眠系统的易化冲动增强所致。与此同时,脑内的清醒系统很可能被额外抑制,从而促进睡眠的发展。