Schoutens E, Koster J P, Arouete A, Tombroff M, Yourassowsky E
a Service de Biologie Clinique , Hôpital Universitaire Brugmann .
b Service de Médecine Interne, Département de Pneumologie , Hôpital Universitaire Brugmann .
Acta Clin Belg. 1971 Jan;26(2):78-94. doi: 10.1080/17843286.1971.11716773.
The authors analyse the bacteriological data gathered by 100 successive tracheal Punctures and compare these results to those obtained by sputum cultures, which had either been collected by routine or when withdrawing the catheter for tracheal aspiration. This plain and not hazardous technique allows to draw the following conclusions : 1) The culture of routinely collected sputum at the patient's bed-side often misleads the physician (6 times on 10) whereas newly expectorated sputum brought immediately to the laboratory more truly shows the tracheo-bronchic flora (valuable results in 75 % of the cases). 2) The tracheal puncture, which reduces the causes of errors, due to the contamination of the sputum by the rhino-pharyngeal flora, to a minimum, particularly is indicated in the following cases : patients who do not expectorate (including suspects of pulmonary tuberculosis), instantly earnest pneumopathia, bad response to applied antibiotic therapy, tests of the true efficiency of an antibiotic therapy. 3) The bacteriological study of these punctures performed on patients, who caused therapeutical problems and who had been submitted to antibiotic therapies evidenced the following data : 40 % of the punctures were sterile, 39 % showed one single germ (18 Gram negative, 16 Gram positive, 2 BK, 3 aspergillus), 15 % showed 2 simultaneous germs and 6 % were not significant.
作者分析了连续100次气管穿刺收集的细菌学数据,并将这些结果与痰培养结果进行比较,痰培养样本是通过常规方式收集的,或者是在拔出气管导管进行抽吸时收集的。这种简单且无风险的技术可以得出以下结论:1)在患者床边常规收集的痰培养结果常常误导医生(10次中有6次),而新咳出的痰立即送检能更真实地显示气管支气管菌群(75%的病例结果有价值)。2)气管穿刺将因鼻咽喉菌群污染痰液导致的误差原因降至最低,尤其适用于以下情况:无咳痰患者(包括疑似肺结核患者)、急性肺炎、对抗生素治疗反应不佳、评估抗生素治疗的实际效果。3)对有治疗问题且接受过抗生素治疗的患者进行的这些穿刺细菌学研究显示了以下数据:40%的穿刺结果无菌,39%显示单一菌种(18种革兰阴性菌、16种革兰阳性菌、2种BK菌、3种曲霉菌),15%显示同时存在两种菌种,6%无意义。