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经气管穿刺抽吸术在肺结核细菌学诊断中的应用价值。

Usefulness of transtracheal puncture and aspiration in the bacteriological diagnosis of pulmonary tuberculosis.

作者信息

Schmerber-Vereerstraeten J, Schoutens E, Lempereur L, Yourassowsky E, De Koster J P

出版信息

Infection. 1977;5(3):132-6. doi: 10.1007/BF01639746.

Abstract

Transtracheal puncture enables two samples of bronchial secretions to be taken-the product of transtracheal aspiration and simultaneously expectorated sputum (obtained in 71% of the cases)-for the purpose of testing for Mycobacterium tuberculosis in cases of suspected pulmonary tuberculosis. Two groups of patients were studied: Group I: 100 patients who were poor expectorators and who all underwent transtracheal puncture; Group II (Control): 100 patients who expectorated well or who had been given gastric lavages immediately on admission. Laboratroy analyses revealed M. tuberculosis in at least one of the samples obtained from each of the 200 patients. The authors compare the efficiency of the methods used within each group and between the two groups. Samples obtained by transtracheal aspiration and simultaneous expectoration (75% of positive results) more often contained M. tuberculosis than the other Group I samples (64% of total positive results; 64% of positive results for spontaneous sputa, 65% for gastric fluids), and as often as the Group II samples (76% of total positive results), particularly the expectoration samples (78% of positive results). Simultaneously expectorated sputum more frequently contained M. tuberculosis (82% of positive results) than transtracheal aspiration (69% of positive results). Transtracheal puncture and/or simultaneous expectoration were the only examinations revealing M. tuberculosis in 34 patients in Group I. Non-specific bacteriological findings are not relevant. However, the authors point out that this technique is not always innocuous (although no serious complications were observed in this series), and that transtracheal puncture must always be carried out by physicians trained in the technique.

摘要

经气管穿刺可获取两份支气管分泌物样本,即经气管吸引物以及同时咳出的痰液(71%的病例可获取),用于疑似肺结核病例中结核分枝杆菌的检测。研究了两组患者:第一组:100例咳痰困难的患者,均接受了经气管穿刺;第二组(对照组):100例咳痰良好或入院后立即接受洗胃的患者。实验室分析显示,从这200例患者中的每例患者获取的至少一份样本中发现了结核分枝杆菌。作者比较了每组内以及两组之间所使用方法的效率。经气管吸引和同时咳出的样本(阳性结果占75%)比第一组的其他样本(总阳性结果的64%;自发痰液阳性结果的64%,胃液阳性结果的65%)更常含有结核分枝杆菌,且与第二组样本(总阳性结果的76%)一样常见,尤其是咳出的样本(阳性结果的78%)。同时咳出的痰液比经气管吸引更常含有结核分枝杆菌(阳性结果的82%比69%)。经气管穿刺和/或同时咳痰是第一组中34例患者唯一检测出结核分枝杆菌的检查。非特异性细菌学发现无关紧要。然而,作者指出,该技术并非总是无害的(尽管本系列中未观察到严重并发症),且经气管穿刺必须始终由接受过该技术培训的医生进行。

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