From the Department of Clinical Sciences/Ophthalmology, Umeå University Hospital, Umeå, Sweden.
From the Department of Clinical Sciences/Ophthalmology, Umeå University Hospital, Umeå, Sweden.
J Cataract Refract Surg. 2016 Jun;42(6):864-9. doi: 10.1016/j.jcrs.2016.02.047.
To analyze the long-term change in light scattering caused by glistenings in hydrophobic acrylic intraocular lenses (IOLs) and the clinical implications on high-contrast and low-contrast visual acuity.
Department of Clinical Sciences/Ophthalmology, Umeå University Hospital, Umeå, Sweden.
Prospective longitudinal case series.
The study comprised patients who had an Acrysof MA60BM IOL implanted between 1997 and 1998. Light scattering from the IOLs was assessed with digital analysis using Scheimpflug photography (Pentacam HR) from both the 10- year and 15-year follow-up. Associations were made between corrected distance visual acuity, low-contrast visual acuity (LCVA) 10.0%, LCVA 2.5%, and the degree of light scattering from the IOL.
At the 15-year follow-up, the majority of the 90 patients had an increased amount of light scattering in all parts measured in the IOL than the patients at the 10-year follow-up. A subgroup of 71 patients without coexisting ocular pathology was selected for the visual function analyses. There was no correlation between light scattering and dioptric power. No clinically relevant reduction in visual function was detected in eyes with more pronounced light scattering. Patients with a larger increase in total light scattering of the IOL at the 15-year follow-up had significantly worse LCVA 2.5% than at the 10-year follow-up (P = .042).
Glistenings continued to increase in hydrophobic acrylic IOLs from 10 to 15 years after surgery. At 15 years, most patients had severe glistenings with a high level of light scattering from the IOL. No clinically significant effect on everyday visual function was found.
Neither author has a financial or proprietary interest in any material or method mentioned.
分析疏水丙烯酸人工晶状体（IOL）中的闪光点引起的光散射的长期变化及其对高对比度和低对比度视力的临床意义。
瑞典于默奥大学医院临床科学/眼科系。
前瞻性纵向病例系列。
该研究包括 1997 年至 1998 年间植入 Acrysof MA60BM IOL 的患者。使用 Scheimpflug 摄影术（Pentacam HR）通过数字分析评估 IOL 的光散射，随访时间为 10 年和 15 年。在 IOL 的光散射程度与矫正距离视力、低对比度视力（LCVA）10.0%、LCVA 2.5%之间建立了关联。
在 15 年的随访中，与 10 年随访相比，90 名患者中的大多数患者 IOL 各部分的光散射量都有所增加。选择了 71 名没有并存眼部疾病的患者进行视觉功能分析。光散射与屈光度之间没有相关性。在光散射更明显的眼中，未检测到视觉功能的临床相关下降。在 15 年随访时，IOL 总光散射增加较多的患者的 LCVA 2.5%明显差于 10 年随访时（P=0.042）。
疏水丙烯酸 IOL 在手术后 10 至 15 年期间，闪光点持续增加。在 15 年时，大多数患者的 IOL 出现严重的闪光点，光散射水平很高。未发现对日常视觉功能有明显影响。
