Rozzini Renzo
Fondazione Poliambulanza, Istituto Ospedaliero.
Monaldi Arch Chest Dis. 2016 Jun 22;84(1-2):727. doi: 10.4081/monaldi.2015.727.
Frailty is a common geriatric syndrome that embodies an elevated risk of catastrophic declines in health and function among older adults. Frailty is a condition associated with ageing with associated weakness, slowing, decreased energy, lower activity, and, when severe, unintended weight loss. As a population ages, a central focus of geriatricians and public health practitioners is to understand, and then beneficially intervene on, the factors and processes that put elders at such risk, especially the increased vulnerability to stressors (e.g. extremes of heat and cold, infection, injury, or even changes in medication) that characterizes many older adults. The syndrome of geriatric frailty is hypothesized to reflect impairments in the regulation of multiple physiologic systems, embodying a lack of resilience to physiologic challenges and thus elevated risk for a range of deleterious endpoints. The empirical assessment of geriatric frailty in individuals seeks to capture this or related features.
衰弱是一种常见的老年综合征，体现了老年人健康和功能出现灾难性衰退的风险升高。衰弱是一种与衰老相关的状况，伴有虚弱、行动迟缓、精力下降、活动减少，严重时还会出现非故意体重减轻。随着人口老龄化，老年医学专家和公共卫生从业者的一个核心关注点是了解并进而有益地干预使老年人面临此类风险的因素和过程，尤其是许多老年人所具有的对压力源（如酷热和严寒、感染、损伤，甚至药物变化）的易感性增加。老年衰弱综合征被认为反映了多个生理系统调节功能的受损，表现为对生理挑战缺乏恢复力，从而导致一系列有害结局的风险升高。对个体老年衰弱的实证评估旨在捕捉这一特征或相关特征。
