老年人虚弱。

Frailty in Older Persons.

机构信息

Gérontopôle, University Hospital of Toulouse, University of Toulouse III-Paul Sabatier, 37 Allées Jules Guesde, Toulouse 31000, France.

Centro Medicina dell'Invecchiamento, Catholic University of the Sacred Heart, Largo Francesco Vito 1, Rome 00168, Italy.

出版信息

Clin Geriatr Med. 2017 Aug;33(3):293-303. doi: 10.1016/j.cger.2017.02.002. Epub 2017 Apr 6.

DOI:10.1016/j.cger.2017.02.002

PMID:28689563

Abstract

Frailty is a clinical state characterized by a decrease of an individual's homeostatic reserves and is responsible for enhanced vulnerability to endogenous and/or exogenous stressors. Such a condition of extreme vulnerability exposes individuals to an increased risk of negative health-related outcomes. Multiple operational definitions of frailty are available in the literature, but none can be indicated as a gold standard. Frailty should be considered a condition of major interest for public health and become the lever for reshaping the obsolete health care systems currently unable to adequately address the clinical needs of aging populations.

摘要

衰弱是一种以个体体内平衡储备减少为特征的临床状态，其使个体易受内源性和/或外源性应激源的影响。这种极度脆弱的状态使个体面临更多的负面健康相关结果的风险。衰弱在文献中有多种操作性定义，但没有一种可以作为金标准。衰弱应被视为公共卫生的主要关注点，并成为重塑目前无法充分满足老龄化人口临床需求的过时医疗保健系统的杠杆。