Kisabay Aysin, Sari Ummu Serpil, Boyaci Recep, Batum Melike, Yilmaz Hikmet, Selcuki Deniz
Department of Neurology, Celal Bayar University, Manisa, Turkey.
Neurol Neurochir Pol. 2016 Jul-Aug;50(4):284-7. doi: 10.1016/j.pjnns.2016.03.007. Epub 2016 Mar 29.
Myasthenia gravis is a disease of neuromuscular junction due to auto-immune destruction of the acetylcholine receptors. Behçet's disease, on the other hand, is a multisystemic vascular-inflammatory disease. Both conditions are not common in the general population although their association has not been reported in the literature. We wanted to present our patient who developed clinical course of myasthenia gravis following discontinuation of medications due to complications of corticosteroid for Behçet's disease. It was observed that clinical findings of myasthenia gravis recovered following restarting steroid treatment and he did not experience attacks of both conditions. Although Myasthenia gravis and Behçet's disease are distinct entities clinically as well as in terms of pathogenesis, they share common physiopathological features and their treatment is based on their common features.
重症肌无力是一种由于乙酰胆碱受体自身免疫性破坏导致的神经肌肉接头疾病。另一方面，白塞病是一种多系统血管炎性疾病。这两种疾病在普通人群中都不常见，尽管它们的关联在文献中尚未有报道。我们想介绍我们的一位患者，该患者因白塞病使用皮质类固醇激素出现并发症而停药后，出现了重症肌无力的临床病程。观察发现，重新开始使用类固醇治疗后，重症肌无力的临床症状有所恢复，且他没有同时出现这两种疾病的发作。尽管重症肌无力和白塞病在临床和发病机制方面都是不同的疾病，但它们具有共同的生理病理特征，且它们的治疗基于这些共同特征。
