Simões Alexandra S, Couto Isabel, Toscano Cristina, Gonçalves Elsa, Póvoa Pedro, Viveiros Miguel, Lapão Luís V
Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon Portugal.
Laboratório de Microbiologia Clínica e Biologia Molecular, Serviço de Patologia Clínica, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, LisbonPortugal; Centro de Estudos de Doenças Crónicas, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, LisbonPortugal.
Front Microbiol. 2016 Jun 7;7:855. doi: 10.3389/fmicb.2016.00855. eCollection 2016.
In Europe, each year, more than four milion patients acquire a healthcare-associated infection (HAI) and almost 40 thousand die as a direct consequence of it. Regardless of many stategies to prevent and control HAIs, they remain an important cause of morbidity and mortality worldwide with a significant economic impact: a recent estimate places it at the ten billion dollars/year. The control of HAIs requires a prompt and efficient identification of the etiological agent and a rapid communication with the clinician. The Microbiology Laboratory has a significant role in the prevention and control of these infections and is a key element of any Infection Control Program. The work of the Microbiology Laboratory covers microbial isolation and identification, determination of antimicrobial susceptibility patterns, epidemiological surveillance and outbreak detection, education, and report of quality assured results. In this paper we address the role and importance of the Microbiology Laboratory in the prevention and control of HAI and in Antibiotic Stewardship Programs and how it can be leveraged when combined with the use of information systems. Additionally, we critically review some challenges that the Microbiology Laboratory has to deal with, including the selection of analytic methods and the proper use of communication channels with other healthcare services.
在欧洲,每年有超过400万患者发生医疗保健相关感染(HAI),其中近4万人直接因此死亡。尽管有许多预防和控制HAIs的策略,但它们仍然是全球发病和死亡的重要原因,并产生重大经济影响:最近的估计将其定为每年100亿美元。控制HAIs需要迅速有效地识别病原体,并与临床医生快速沟通。微生物实验室在预防和控制这些感染方面发挥着重要作用,是任何感染控制计划的关键要素。微生物实验室的工作包括微生物分离和鉴定、抗菌药物敏感性模式的测定、流行病学监测和暴发检测、教育以及保证结果的报告。在本文中,我们探讨了微生物实验室在预防和控制HAI以及抗生素管理计划中的作用和重要性,以及当与信息系统结合使用时如何发挥其作用。此外,我们批判性地审视了微生物实验室必须应对的一些挑战,包括分析方法的选择以及与其他医疗服务机构沟通渠道的正确使用。