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颈部结核性淋巴结炎:孟加拉国一家二级医院患者的临床人口统计学特征

Cervical Tuberculous Lymphadenitis: Clinico-demographic Profiles of Patients in a Secondary Level Hospital of Bangladesh.

作者信息

Kamal Mohammad Shah, Hoque Md Hafiz Ehsanul, Chowdhury Fazle Rabbi, Farzana Rubina

机构信息

Mohammad Shah Kamal, FCPS (ENT). Junior Consultant (ENT), Shaheed Shamsuddin Ahmed Hospital, Sylhet, Bangladesh.

Md. Hafiz Ehsanul Hoque, PhD. MAG Osmani Medical College& Hospital, Sylhet, Bangladesh.

出版信息

Pak J Med Sci. 2016 May-Jun;32(3):608-12. doi: 10.12669/pjms.323.9550.

Abstract

OBJECTIVE

Tuberculosis (TB) is a major public health problem in Bangladesh since long. The present incidence and prevalence rates of all forms of TB are 227 and 404/100,000 population respectively. The aim of this study was to find out the clinical characteristics of involved cervical lymph nodes, demographic characteristics of the patients and response to treatment of Cervical Tuberculous Lymphadenitis (CTL) cases.

METHODS

A prospective study was performed in Shaheed Shamsuddin Ahmed Hospital, Sylhet, Bangladesh from June 2012 to June 2014. Total 65 patients having CTL attending outpatient department of the hospital were enrolled.

RESULTS

Age of the patients ranged from 5 to 60 years with a mean of 25.6 years. Two third (67.7%) of the patients were female. Male: Female ratio was 1:2.1. More than half of the patients came from rural areas (53.8%) and from low socio-economic conditions (58.5%). Most of the patients presented with unilateral (87.7%), multiple (82.3%), matted (68.6%) lymph nodes, <3cm diameter (54%), commonly in right side (57.9%). Abscess was found in 21.5% cases. Discharging sinus was found in 9.2% cases. Most commonly involved lymph node group was level V (59.4%) followed by level II (42.2%). Systemic features were found in 63.07% patients. Associated lung lesion was found in 3.1% cases. FNAC was found positive for tuberculosis in 83.9% cases. Most of the patients (78.46%) were cured with six months anti-tubercular chemotherapy.

CONCLUSIONS

Early diagnosis and treatment is critical in reducing the overall prevalence. It is essential to have awareness regarding common presentations of cervical tuberculous lymphadenitis among the general population as well as healthcare professionals working in the resource poor primary and secondary level hospitals.

摘要

目的

长期以来,结核病一直是孟加拉国的一个主要公共卫生问题。目前所有类型结核病的发病率和患病率分别为227/10万人口和404/10万人口。本研究的目的是找出受累颈部淋巴结的临床特征、患者的人口统计学特征以及颈部结核性淋巴结炎(CTL)病例的治疗反应。

方法

2012年6月至2014年6月在孟加拉国锡尔赫特的谢赫·沙姆斯丁·艾哈迈德医院进行了一项前瞻性研究。共有65例患有CTL的患者在该医院门诊部就诊并被纳入研究。

结果

患者年龄在5至60岁之间,平均年龄为25.6岁。三分之二(67.7%)的患者为女性。男女比例为1:2.1。超过一半的患者来自农村地区(53.8%)且社会经济条件较差(58.5%)。大多数患者表现为单侧(87.7%)、多个(82.3%)、融合(68.6%)的淋巴结,直径<3cm(54%),常见于右侧(57.9%)。21.5%的病例发现有脓肿。9.2%的病例发现有排脓窦道。最常受累的淋巴结组是Ⅴ级(59.4%),其次是Ⅱ级(42.2%)。63.07%的患者有全身症状。3.1%的病例发现有肺部相关病变。83.9%的病例细针穿刺抽吸活检(FNAC)结果显示结核阳性。大多数患者(78.46%)通过六个月的抗结核化疗治愈。

结论

早期诊断和治疗对于降低总体患病率至关重要。普通人群以及在资源匮乏的基层和二级医院工作的医护人员必须了解颈部结核性淋巴结炎的常见表现。

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