Riemer Daniel, Hirapara Pradipbhai, Das Shoubhik
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstr. 2, 37077, Göttingen, Germany.
ChemSusChem. 2016 Aug 9;9(15):1916-20. doi: 10.1002/cssc.201600521. Epub 2016 Jul 4.
Synthesis of carbamates directly from amines using CO2 as the carbon source is a straightforward and sustainable approach. Herein, we describe a highly effective and chemoselective methodology for the synthesis of carbamates at room temperature and atmospheric pressure. This methodology can also be applied to protect the amino group in amino acids and peptides, and also to synthesize important pharmaceuticals.
使用二氧化碳作为碳源直接从胺类合成氨基甲酸酯是一种直接且可持续的方法。在此，我们描述了一种在室温和大气压下合成氨基甲酸酯的高效且化学选择性的方法。该方法还可用于保护氨基酸和肽中的氨基，以及合成重要的药物。
