[异索拉胺和曲美托嗪对生长中大鼠心肌在血液性缺氧时烟酰胺辅酶含量的影响]
[Influence of isolanide and trasicor on the content of nicotinamide coenzymes in the myocardium of growing rats in hemic hypoxia].
作者信息
Viktorov A P, Kurilina I A, Ljutkevich V F
出版信息
Farmakol Toksikol. 1978 Jun-Aug;41(4):401-5.
PMID:27378
Abstract
Hemic hypoxia was produced in 7,30-day and 3--5-month old (adult) rats through introduction of sodium nitrite (100 mg/kg) with subsequent determination of the nicotinamide co-enzymes content in the myocardium. The effect of combined and separate application of the cardiac glycoside isolanide and beta-adrenoblocking agent trasicor under hypoxia at early stages of post-natal ontogenesis is shown.
摘要
通过注射亚硝酸钠（100毫克/千克）在7只30日龄和3 - 5月龄（成年）大鼠中造成血液性缺氧，随后测定心肌中烟酰胺辅酶的含量。研究显示了在出生后个体发育早期缺氧情况下，强心苷异索兰和β-肾上腺素能阻滞剂曲司氯铵联合及单独应用的效果。
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