脂肪酸生物合成的调控：从泌乳兔乳腺中纯化乙酰辅酶A羧化酶的简单方法，以及其被内源性环磷酸腺苷依赖性和非依赖性蛋白激酶活性磷酸化的过程。 - Suppr

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超能文献

The regulation of fatty acid biosynthesis: simple procedure for the purification of acetyl CoA carboxylase from lactating rabbit mammary gland, and its phosphorylation by endogenous cyclic AMP-dependent and -independent protein kinase activities.

作者信息

Hardie D G, Cohen P

出版信息

FEBS Lett. 1978 Jul 1;91(1):1-7. doi: 10.1016/0014-5793(78)80005-2.

DOI:10.1016/0014-5793(78)80005-2

PMID:27383

Abstract

摘要

相似文献

The regulation of fatty acid biosynthesis: simple procedure for the purification of acetyl CoA carboxylase from lactating rabbit mammary gland, and its phosphorylation by endogenous cyclic AMP-dependent and -independent protein kinase activities.脂肪酸生物合成的调控：从泌乳兔乳腺中纯化乙酰辅酶A羧化酶的简单方法，以及其被内源性环磷酸腺苷依赖性和非依赖性蛋白激酶活性磷酸化的过程。

FEBS Lett. 1978 Jul 1;91(1):1-7. doi: 10.1016/0014-5793(78)80005-2.

Reversible phosphorylation and inactivation of acetyl-CoA carboxylase from lactating rat mammary gland by cyclic AMP-dependent protein kinase.环磷酸腺苷依赖性蛋白激酶对泌乳大鼠乳腺中乙酰辅酶A羧化酶的可逆磷酸化作用及失活

Eur J Biochem. 1980 Sep;110(1):167-77. doi: 10.1111/j.1432-1033.1980.tb04852.x.

Isolation of three cyclic-AMP-independent acetyl-CoA carboxylase kinases from lactating rat mammary gland and characterization of their effects on enzyme activity.从泌乳大鼠乳腺中分离出三种不依赖环磷酸腺苷的乙酰辅酶A羧化酶激酶，并对其对酶活性的影响进行表征。

Eur J Biochem. 1984 Jun 15;141(3):617-27. doi: 10.1111/j.1432-1033.1984.tb08237.x.

Characterization of the phosphorylation of rat mammary ATP-citrate lyase and acetyl-CoA carboxylase by Ca2+ and calmodulin-dependent multiprotein kinase and Ca2+ and phospholipid-dependent protein kinase.大鼠乳腺ATP-柠檬酸裂解酶和乙酰辅酶A羧化酶的磷酸化特性：由钙离子和钙调蛋白依赖性多蛋白激酶以及钙离子和磷脂依赖性蛋白激酶介导

Eur J Biochem. 1986 Jun 16;157(3):553-61. doi: 10.1111/j.1432-1033.1986.tb09702.x.

Cyclic AMP-dependent protein kinase in mammary tissue of the lactating rat. Activity ratio and responsiveness of the target enzymes acetyl-CoA carboxylase and glycogen phosphorylase to beta-adrenergic stimulation.泌乳大鼠乳腺组织中的环磷酸腺苷依赖性蛋白激酶。靶酶乙酰辅酶A羧化酶和糖原磷酸化酶对β-肾上腺素能刺激的活性比率及反应性。

Biochem J. 1990 Feb 1;265(3):769-75. doi: 10.1042/bj2650769.

The role of phosphorylation/dephosphorylation of acetyl-CoA carboxylase in the regulation of mammalian fatty acid biosynthesis.乙酰辅酶A羧化酶的磷酸化/去磷酸化在哺乳动物脂肪酸生物合成调控中的作用。

Biochem Soc Trans. 1986 Jun;14(3):559-62. doi: 10.1042/bst0140559.

Acetyl-CoA carboxylase and fatty acid synthase from lactating rabbit and rat mammary gland.来自泌乳兔和大鼠乳腺的乙酰辅酶A羧化酶和脂肪酸合酶。

Methods Enzymol. 1981;71 Pt C:26-33. doi: 10.1016/0076-6879(81)71005-x.

Dephosphorylation and activation of acetyl-CoA carboxylase from lactating rabbit mammary gland.泌乳兔乳腺中乙酰辅酶A羧化酶的去磷酸化与激活

FEBS Lett. 1979 Jul 15;103(2):333-8. doi: 10.1016/0014-5793(79)81356-3.

The role of acetyl-CoA carboxylase phosphorylation in the control of mammary gland fatty acid synthesis during the starvation and re-feeding of lactating rats.乙酰辅酶A羧化酶磷酸化在泌乳大鼠饥饿和重新喂食期间乳腺脂肪酸合成调控中的作用。

Biochem J. 1986 Jul 1;237(1):85-91. doi: 10.1042/bj2370085.

Purification and physicochemical properties of fatty acid synthetase and acetyl-CoA carboxylase from lactating rabbit mammary gland.泌乳兔乳腺中脂肪酸合成酶和乙酰辅酶A羧化酶的纯化及理化性质

Eur J Biochem. 1978 Dec 1;92(1):25-34. doi: 10.1111/j.1432-1033.1978.tb12719.x.

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Curr Opin Hematol. 2024 Sep 1;31(5):217-223. doi: 10.1097/MOH.0000000000000820. Epub 2024 May 7.

AMP-activated protein kinase - a journey from 1 to 100 downstream targets.腺苷酸活化蛋白激酶——下游靶点的 100 之旅。

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Cloning and characterization of the 5' end and promoter region of the chicken acetyl-CoA carboxylase gene.鸡乙酰辅酶A羧化酶基因5'端及启动子区域的克隆与特性分析

Biochem J. 1996 Mar 1;314 ( Pt 2)(Pt 2):613-9. doi: 10.1042/bj3140613.

Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site.有证据表明胰岛素通过增加特定位点的磷酸化作用来激活脂肪细胞乙酰辅酶A羧化酶。

Biochem J. 1982 Jan 15;202(1):77-86. doi: 10.1042/bj2020077.

Regulation of acetyl-coA carboxylase: properties of coA activation of acetyl-coA carboxylase.乙酰辅酶A羧化酶的调节：辅酶A对乙酰辅酶A羧化酶的激活特性

Proc Natl Acad Sci U S A. 1980 Jun;77(6):3351-5. doi: 10.1073/pnas.77.6.3351.

Both insulin and epidermal growth factor stimulate lipogenesis and acetyl-CoA carboxylase activity in isolated adipocytes. Importance of homogenization procedure in avoiding artefacts in acetyl-CoA carboxylase assay.胰岛素和表皮生长因子均可刺激分离的脂肪细胞中的脂肪生成及乙酰辅酶A羧化酶活性。乙酰辅酶A羧化酶测定中匀浆程序对于避免人为误差的重要性。

Biochem J. 1986 Mar 1;234(2):279-84. doi: 10.1042/bj2340279.

Evidence that glucagon-mediated inhibition of acetyl-CoA carboxylase in isolated adipocytes involves increased phosphorylation of the enzyme by cyclic AMP-dependent protein kinase.在分离的脂肪细胞中，胰高血糖素介导的对乙酰辅酶A羧化酶的抑制作用涉及环磷酸腺苷依赖性蛋白激酶使该酶磷酸化增加的证据。

Biochem J. 1985 Feb 15;226(1):139-45. doi: 10.1042/bj2260139.

Isolation and identification of acetyl-CoA carboxylase from rainbow trout (Salmo gairdneri) liver.虹鳟（萨氏虹鳟）肝脏中乙酰辅酶A羧化酶的分离与鉴定。

Lipids. 1989 Mar;24(3):187-92. doi: 10.1007/BF02535233.

Adrenaline and the regulation of acetyl-coenzyme A carboxylase in rat epididymal adipose tissue. Inactivation of the enzyme is associated with phosphorylation and can be reversed on dephosphorylation.肾上腺素与大鼠附睾脂肪组织中乙酰辅酶A羧化酶的调节。该酶的失活与磷酸化有关，去磷酸化后可逆转。

Biochem J. 1979 Oct 15;184(1):23-32. doi: 10.1042/bj1840023.

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