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[Treatment and prognosis of sacrococcygeal chordoma--study of bone tumor registry in Japan].

作者信息

Osaka S, Toriyama S

机构信息

Department of Orthopaedic Surgery, Nihon University School of Medicine, Tokyo, Japan.

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1989 Apr;63(4):240-4.

PMID:2738424
Abstract

Prognosis of chordoma arising in the sacrococcygeal area is difficult to assess because of the small number cases and lack of statistics in Japan. From the bone tumor registry we selected records on sacrococcygeal chordoma cases and sent a questionnaire to many hospitals regarding staging, surgical approach, surgical procedure, radiotherapy, chemotherapy, complications and prognosis of this tumor. The results of the questionnaire (32 cases) showed that combined surgery and radiotherapy were the best methods. This survival rate was 85% in five years and 43% in ten years. In the surgical procedure the extralesional excision resulted in a high recurrence rate (73%) three years after operation, and in the case of intralesional excision an even higher rate (91%). We assume this is a problem of the excisional method. In the staging system, the intracompartment tumors have a better prognosis. Early stage discovery and surgical treatment is of vital importance.

摘要

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引用本文的文献

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Sacral Insufficiency Fractures are Common After High-dose Radiation for Sacral Chordomas Treated With or Without Surgery.对于接受或未接受手术治疗的骶骨脊索瘤,在大剂量放疗后,骶骨应力性骨折很常见。
Clin Orthop Relat Res. 2016 Mar;474(3):766-72. doi: 10.1007/s11999-015-4566-5. Epub 2015 Sep 23.
2
Clinical significance of a wide excision policy for sacrococcygeal chordoma.骶尾部脊索瘤广泛切除策略的临床意义
J Cancer Res Clin Oncol. 2006 Apr;132(4):213-8. doi: 10.1007/s00432-005-0067-3. Epub 2005 Dec 16.