与对照组相比，幼年特发性关节炎患儿的身体活动情况。
Physical activity in children with Juvenile Idiopathic Arthritis compared to controls.
作者信息
Bos G J F Joyce, Lelieveld Otto T H M, Armbrust Wineke, Sauer Pieter J J, Geertzen Jan H B, Dijkstra Pieter U
机构信息
Department of Rehabilitation Medicine, University of Groningen, University Medical Center Groningen, PO Box 30001, 9700 RB, Groningen, The Netherlands.
Department of Pediatric Rheumatology, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, PO Box 30001, 9700 RB, Groningen, The Netherlands.
出版信息
Pediatr Rheumatol Online J. 2016 Jul 7;14(1):42. doi: 10.1186/s12969-016-0102-8.
BACKGROUND
To compare physical activity (PA) in children with juvenile idiopathic arthritis (JIA) with controls and to analyse the effect of disease specific factors on PA in children with JIA treated according to current treatment regimes.
METHODS
PA was measured with a 7-day activity diary and expressed as physical activity level (PAL). Moderate to vigorous physical activity (MVPA) (hours/day) and sedentary time (hours/day) was determined. In children with JIA, medication, the number of swollen and/or painful joints, disease activity, functional ability, pain and well-being was determined. Multivariate regression analysis was performed to analyze differences in PA between JIA and controls, adjusted for influences of age, gender, season, Body Mass Index (BMI) and to analyze predictors of PA in JIA patients.
RESULTS
Seventy-six children with JIA (26 boys and 50 girls, mean ± SD age 10.0 ± 1.4 years) and 131 controls (49 boys and 82 girls, mean ± SD age 10.4 ± 1.2 years) participated in this study. Children with JIA had a significantly lower PAL (0.10, p = 0.01) corrected for age, BMI, gender and season. They spent less time in MVPA (0.41 h/day, p = 0.06) and had a significantly higher mean time spent in sedentary activities (0.59 h/day, p 0.02) compared to controls. The activity level of children with JIA was related to age, gender, season, feeling of well-being and pain.
CONCLUSION
Children with JIA have a lower PAL, spent less time in MVPA and spent more time on sedentary activities compared to controls despite current medical treatment and PA encouragement.
TRIAL REGISTRATION
Data of the children with JIA are from the Rheumates@work study ISRCTN92733069 .
背景
比较幼年特发性关节炎（JIA）患儿与对照组儿童的身体活动（PA）情况，并分析疾病特异性因素对按照当前治疗方案治疗的JIA患儿PA的影响。
方法
采用7天活动日记测量PA，并表示为身体活动水平（PAL）。确定中度至剧烈身体活动（MVPA）（小时/天）和久坐时间（小时/天）。对于JIA患儿，确定其用药情况、肿胀和/或疼痛关节的数量、疾病活动度、功能能力、疼痛和健康状况。进行多变量回归分析，以分析JIA患儿与对照组之间PA的差异，并对年龄、性别、季节、体重指数（BMI）的影响进行校正，同时分析JIA患者PA的预测因素。
结果
76名JIA患儿（26名男孩和50名女孩，平均±标准差年龄10.0±1.4岁）和131名对照组儿童（49名男孩和82名女孩，平均±标准差年龄10.4±1.2岁）参与了本研究。校正年龄、BMI、性别和季节后，JIA患儿的PAL显著更低（0.10，p = 0.01）。与对照组相比，他们在MVPA上花费的时间更少（0.41小时/天，p = 0.06），而久坐活动的平均时间显著更长（0.59小时/天，p < 0.02）。JIA患儿的活动水平与年龄、性别、季节、幸福感和疼痛有关。
结论
尽管有当前的药物治疗和PA鼓励措施，但与对照组相比，JIA患儿的PAL更低，在MVPA上花费的时间更少，在久坐活动上花费的时间更多。
试验注册
JIA患儿的数据来自Rheumates@work研究，ISRCTN92733069 。
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