Mohamed Buhary Thajunnisha, Gayed Sedki Latif, Hafeez Irfan
Department of GUM, East Lancashire Hospitals NHS Trust, Burnley, UK.
Department of General Medicine, East Lancashire Hospitals NHS Trust, Blackburn, UK.
BMJ Case Rep. 2016 Jul 7;2016:bcr2016215686. doi: 10.1136/bcr-2016-215686.
Disseminated atypical Mycobacterium infection is a well-known opportunistic infection in HIV-infected patients with advanced immune deficiency before the introduction of combination antiretroviral therapy. Although the disseminated infection is now rare, few cases of localised infections are reported. A 38-year-old man was diagnosed with HIV infection during asymptomatic sexual health screening. Although he was asymptomatic on diagnosis, he had advanced immunodeficiency; therefore, combination antiretroviral therapy was started immediately. After 5 months of treatment, he developed pericardial effusion. Mycobacterium was detected from a culture of the pericardial fluid and Mycobacterium avium complex was identified using a gene probe test. He was treated with combination therapy for Mycobacterium infection and he fully recovered. Treatment continued for 4 years until he achieved adequate immune recovery.
播散性非典型分枝杆菌感染是在联合抗逆转录病毒疗法出现之前，晚期免疫缺陷的HIV感染患者中一种众所周知的机会性感染。虽然现在播散性感染很少见，但仍有少数局部感染的病例报道。一名38岁男性在无症状性健康筛查中被诊断为HIV感染。虽然诊断时他无症状，但已有严重免疫缺陷；因此，立即开始联合抗逆转录病毒治疗。治疗5个月后，他出现了心包积液。从心包积液培养物中检测到分枝杆菌，并通过基因探针试验鉴定为鸟分枝杆菌复合群。他接受了分枝杆菌感染的联合治疗，完全康复。治疗持续了4年，直到他实现了充分的免疫恢复。
