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以背部疼痛或腿部疼痛为主的患者接受显微镜下腰椎手术的短期和长期结果

Short- and Long-Term Outcome of Microscopic Lumbar Spine Surgery in Patients with Predominant Back or Predominant Leg Pain.

作者信息

Stienen Martin N, Joswig Holger, Smoll Nicolas R, Corniola Marco V, Schaller Karl, Hildebrandt Gerhard, Gautschi Oliver P

机构信息

Department of Neurosurgery and Faculty of Medicine, University Hospital Geneva, Geneva, Switzerland.

Department of Neurosurgery, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.

出版信息

World Neurosurg. 2016 Sep;93:458-465.e1. doi: 10.1016/j.wneu.2016.06.120. Epub 2016 Jul 5.

Abstract

OBJECTIVE

This study assessed whether predominant back pain (pBP) represents a negative outcome predictor in patients undergoing microscopic spine surgery without fusion for a lumbar disc herniation (LDH) or spinal stenosis (LSS).

METHODS

Retrospective analysis of prospectively collected data on consecutive patients with LDH or LSS at 2 centers. Patients with visual analog scale (VAS) back pain ≥VAS leg pain were assigned to the pBP group, and compared with patients with predominant VAS leg pain (pLP). Outcome measures included the Roland-Morris Disability Index (RMDI), Oswestry Disability Index (ODI), health-related quality of life measures, Short-Form (SF)-12 Physical Component Summary (PCS), and EuroQol (EQ-5D) index at 3 days, 6 weeks (W6), 6 months, and 1 year postoperatively.

RESULTS

A total of 325 patients (154 [47.4%] with pBP and 171 [52.6%] with pLP) were included. Patients with pBP were about 6 years older and more often had LSS. There was no significant difference between the group means of the RMDI, ODI, SF-12 PCS, or EQ-5D at any postoperative time point. The most improvement was observed until the W6 follow-up with little or no improvement thereafter up to 1 year postoperatively. Patients with pBP were as likely as patients with pLP to be W6 responders on the RMDI (odds ratio [OR], 0.91; 95% confidence interval [CI], 0.38-2.16; P = 0.831), ODI (OR, 1.00; 95% CI 0.52-1.92; P = 0.996), SF-12 PCS (OR, 1.09; 95% CI 0.58-2.04; P = 0.791), and EQ-5D (OR, 0.62; 95% CI 0.32-1.21; P = 0.164). Disease-specific subgroup analyses confirmed the results.

CONCLUSIONS

The present data suggest that patients with pBP have comparable functional and health-related quality of life outcomes after surgery for LDH or LSS with those of patients with pLP.

摘要

目的

本研究评估了在接受腰椎间盘突出症(LDH)或腰椎管狭窄症(LSS)显微脊柱手术且未行融合术的患者中,以背痛为主(pBP)是否代表负面预后预测因素。

方法

对两个中心连续的LDH或LSS患者前瞻性收集的数据进行回顾性分析。视觉模拟量表(VAS)背痛评分≥VAS腿痛评分的患者被分配到pBP组,并与以VAS腿痛为主(pLP)的患者进行比较。结局指标包括术后3天、6周(W6)、6个月和1年时的罗兰-莫里斯残疾指数(RMDI)、奥斯威斯残疾指数(ODI)、健康相关生活质量指标、简短形式(SF)-12身体成分总结(PCS)和欧洲五维度健康量表(EQ-5D)指数。

结果

共纳入325例患者(154例[47.4%]为pBP,171例[52.6%]为pLP)。pBP患者年龄约大6岁,且更常患有LSS。在任何术后时间点,RMDI、ODI、SF-12 PCS或EQ-5D的组均值之间均无显著差异。术后直至W6随访时改善最为明显,此后直至术后1年几乎没有改善。pBP患者在RMDI(优势比[OR],0.91;95%置信区间[CI],0.38 - 2.16;P = 0.831)、ODI(OR,1.00;95% CI 0.52 - 1.92;P = 0.996)、SF-12 PCS(OR,1.09;95% CI 0.58 - 2.04;P = 0.791)和EQ-5D(OR,0.62;95% CI 0.32 - 1.21;P = 0.164)方面成为W6应答者的可能性与pLP患者相同。疾病特异性亚组分析证实了该结果。

结论

目前的数据表明,对于LDH或LSS手术患者,pBP患者与pLP患者术后的功能和健康相关生活质量结局相当。

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