Moisés J A, Xaubet A, Agustí C, Picado C, Marín A, Agustí-Vidal A
Med Clin (Barc). 1989 Apr 1;92(12):454-6.
The cell preparations of 199 bronchoalveolar lavages (BAL) were reviewed to evaluate the meaning of the presence of mastocytes for the diagnosis of diffuse interstitial lung diseases. The study population consisted of 41 control individuals, 10 with extrinsic allergic alveolitis (EAA), 55 with sarcoidosis 38 with asbestosis, 25 with pulmonary fibrosis associated to collagen diseases, 18 with idiopathic pulmonary fibrosis and 12 with carcinomatous lymphangitis. Mastocytes were predominantly found in patients with EAA (8 of 10 cases) and in some cases of sarcoidosis and idiopathic pulmonary fibrosis. The rate of mastocytes in the patients with EAA was significantly higher than in the other groups (p less than 0.001). The presence of mastocytes in the BAL is particularly suggestive of EAA; rates higher than 3% are only found in this condition.
回顾了199份支气管肺泡灌洗（BAL）的细胞制剂，以评估肥大细胞的存在对弥漫性间质性肺疾病诊断的意义。研究人群包括41名对照个体、10名外源性过敏性肺泡炎（EAA）患者、55名结节病患者、38名石棉沉着病患者、25名与胶原疾病相关的肺纤维化患者、18名特发性肺纤维化患者和12名癌性淋巴管炎患者。肥大细胞主要见于EAA患者（10例中有8例）以及部分结节病和特发性肺纤维化病例。EAA患者中的肥大细胞比例显著高于其他组（p<0.001）。BAL中存在肥大细胞特别提示EAA；仅在这种情况下发现比例高于3%。
