Orlova G P, Zhuravlev A V
Klin Med (Mosk). 1990 Jan;68(1):69-73.
Cytological and immunological investigations of bronchoalveolar lavage fluid (BLF) have been performed in 87, 27, 32 and 94 patients with fibrosing alveolitis (FA), exogenous allergic alveolitis (EAA), histiocytosis and pulmonary sarcoidosis (PS), respectively. The diseases appeared to demonstrate significant differences in BLF cell composition and relations between T-lymphocyte theophyllin-resistent and theophyllin-sensitive subpopulations. The findings can be applied in differential diagnosis of disseminated processes in the lungs. The number of neutrophils and the subpopulations correlation in FA and EAA may serve criteria of the disease activity and adequacy of the treatment administered.
分别对87例纤维化肺泡炎（FA）、27例外源性过敏性肺泡炎（EAA）、32例组织细胞增多症和94例肺结节病（PS）患者进行了支气管肺泡灌洗（BLF）的细胞学和免疫学研究。这些疾病在BLF细胞组成以及T淋巴细胞茶碱抵抗亚群和茶碱敏感亚群之间的关系上似乎存在显著差异。这些发现可应用于肺部弥漫性病变的鉴别诊断。FA和EAA中中性粒细胞的数量以及亚群相关性可作为疾病活动度和所给予治疗是否恰当的标准。
