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经导管主动脉瓣植入自膨胀式人工瓣膜后经皮冠状动脉介入治疗的发生率、可行性及结果。单中心经验结果

Incidence, feasibility and outcome of percutaneous coronary intervention after transcatheter aortic valve implantation with a self-expanding prosthesis. Results from a single center experience.

作者信息

Allali Abdelhakim, El-Mawardy Mohamed, Schwarz Bettina, Sato Takao, Geist Volker, Toelg Ralph, Richardt Gert, Abdel-Wahab Mohamed

机构信息

Heart Center, Segeberger Kliniken GmbH, Academic Teaching Hospital for the Universities of Kiel, Lübeck and Hamburg, Bad Segeberg, Germany.

Heart Center, Segeberger Kliniken GmbH, Academic Teaching Hospital for the Universities of Kiel, Lübeck and Hamburg, Bad Segeberg, Germany.

出版信息

Cardiovasc Revasc Med. 2016 Sep;17(6):391-8. doi: 10.1016/j.carrev.2016.05.010. Epub 2016 Jun 17.

Abstract

OBJECTIVES

Percutaneous coronary intervention (PCI) after transcatheter aortic valve implantation (TAVI) can become technically challenging after implantation of the self-expanding Medtronic CoreValve (MCV) device, which completely covers the aortic root. The aim of this study was to report on the incidence, feasibility and outcome of PCI after TAVI with the MCV device.

METHODS

Between 2007 and 2014, all patients subjected to PCI after MCV implantation in a single-center institutional TAVI database were retrospectively identified. Clinical, angiographic and procedural characteristics were reviewed and analyzed.

RESULTS

We identified a total of 17 patients (5.7%) treated with 24 PCI procedures for 29 lesions at a median of 17.7months (range 1-72) after MCV implantation. The mean age was 79.7±6.8years and the mean logistic EuroSCORE was 30.3%±18.9%. Nine procedures were performed for patients with acute coronary syndrome. 89.6% of the treated lesions were of type B2/C and 79.3% were de novo ones. A median of one guiding catheter was necessary to intubate the target coronary ostium (range 1-10) and 95% of the lesions on the left coronary artery were treated through a Judkins catheter. In one primary PCI for STEMI the intubation of the right coronary ostium was not successful. Final procedural success was obtained in 95.8%, and peri-procedural death occurred in one patient.

CONCLUSIONS

The need for PCI after MCV is not uncommon and is mostly related to coronary artery disease progression. PCI after MCV is usually feasible and safe, but coronary intubation in an emergency setting can be challenging.

摘要

目的

经导管主动脉瓣植入术(TAVI)后进行经皮冠状动脉介入治疗(PCI),在植入自膨胀美敦力CoreValve(MCV)装置后可能会在技术上具有挑战性,该装置完全覆盖主动脉根部。本研究的目的是报告使用MCV装置进行TAVI后PCI的发生率、可行性和结果。

方法

回顾性分析2007年至2014年在单中心机构TAVI数据库中接受MCV植入术后进行PCI的所有患者。对临床、血管造影和手术特征进行回顾和分析。

结果

我们共确定了17例患者(5.7%),在MCV植入术后中位17.7个月(范围1 - 72个月)接受了24次PCI手术,治疗29处病变。平均年龄为79.7±6.8岁,平均逻辑欧洲心脏手术风险评估系统(EuroSCORE)为30.3%±18.9%。9例手术是针对急性冠状动脉综合征患者进行的。89.6%的治疗病变为B2/C型,79.3%为新发病变。插入目标冠状动脉口中位需要1根引导导管(范围1 - 10),95%的左冠状动脉病变通过Judkins导管进行治疗。在1例ST段抬高型心肌梗死(STEMI)的直接PCI中,右冠状动脉口插管未成功。最终手术成功率为95.8%,1例患者发生围手术期死亡。

结论

MCV植入术后进行PCI并不罕见,且大多与冠状动脉疾病进展有关。MCV植入术后进行PCI通常是可行且安全的,但在紧急情况下进行冠状动脉插管可能具有挑战性。

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