van Ree J W, van Weel C, Arts H, van den Hoogen H
Ned Tijdschr Geneeskd. 1989 May 27;133(21):1073-6.
Correlation exists between the occurrence of a transient ischemic attack (TIA) and a cerebrovascular accident (CVA). The strength of this correlation however is a point for debate. We studied the sequential relation between the occurrence of TIA and CVA in patients over 50 years in general practice. Based on Continuous Morbidity Registration (CMR) in four general practices we analysed the morbidity in patients who presented symptoms of TIA and (or) CVA during the period 1971-1983. In this period a TIA was diagnosed in 134 persons and a CVA in 214 persons. The maximal observation period of the TIA patients after presentation of the symptoms was 12 1/2 years. In 8% of the CVA cases a TIA had been diagnosed in the period preceding the CVA. Of the TIA patients 13% developed a CVA in the subsequent observation period, half of them within two years after the TIA diagnosis. Comparison of the incidence rate of CVA in the general population with that in the population with a TIA reveals that a CVA development is about six times more frequent in the latter. This higher risk has only a relative meaning because the absolute number of cases is small.
短暂性脑缺血发作(TIA)与脑血管意外(CVA)的发生之间存在相关性。然而,这种相关性的强度是一个有争议的问题。我们在一般医疗实践中研究了50岁以上患者中TIA和CVA发生的先后顺序关系。基于四个一般医疗实践中的连续发病率登记(CMR),我们分析了1971年至1983年期间出现TIA和(或)CVA症状的患者的发病率。在此期间,134人被诊断为TIA,214人被诊断为CVA。TIA患者出现症状后的最长观察期为12.5年。在8%的CVA病例中,在CVA发生前的时期曾被诊断为TIA。在TIA患者中,13%在随后的观察期内发生了CVA,其中一半在TIA诊断后的两年内发生。将一般人群中CVA的发病率与有TIA的人群中的发病率进行比较,发现后者发生CVA的频率大约高六倍。这种较高的风险仅具有相对意义,因为病例的绝对数量很少。