Blok G J, Flikweert D C, Nauta J J, Leezenberg J A, Snel A M, van der Baan S
Ned Tijdschr Geneeskd. 1989 May 27;133(21):1076-80.
A statistical analysis was made of data concerning diagnosis of IgE-mediated allergy in the upper respiratory tract in 292 patients. It appears that screening for an IgE-mediated allergy can be performed with a limited number of skin tests (rye grass, timothy, birch, house dust mite and cat). In this study a larger number of skin tests (15 instead of 5) and investigation of specific IgE (RAST) yielded little additional information (in 2% and 3% of the patients, respectively). When indicated, an extended series of skin tests, immuno-assay (total IgE and specific IgE) and eosinophil counts in the serum and nasal smear should be performed.