Blom H J, Mulder M F, Verweij W M
Ned Tijdschr Geneeskd. 1989 May 27;133(21):1080-3.
In order to obtain adequate normal values for arterial blood gas values, the effect of aging and activity was investigated by cross-sectional selection in an in-patient population of 108 patients aged between 20 and 90 years. The patients were free of pulmonary, cardiac and metabolic disease. Smoking and obesity were tolerated up to specified limits. Arterial blood was obtained during standardised resting and active states. The results show a clinically important and highly significant (p less than 0.001) decline of the oxygen tension (PaO2) with age and also a considerable effect of minor activity (p less than 0.01) on blood gas values. However, the relationship of both oxygen tension and oxygen saturation with age is not a linear function as suggested in previous studies. For the interpretation of arterial oxygen tension values or to define hypoxaemia, only normal values related to age and activity should be used. In the elderly, low levels of PaO2 are encountered regularly. Determination of the oxygen saturation may be helpful, especially in differentiating between a normal and a pathological state.
为了获取动脉血气值的充分正常参考值，通过横断面研究，对108名年龄在20至90岁之间的住院患者进行了调查，以研究年龄和活动对其的影响。这些患者无肺部、心脏及代谢疾病。吸烟和肥胖在特定限度内可被接受。在标准化的静息和活动状态下采集动脉血。结果显示，氧分压（PaO2）随年龄增长出现具有临床意义且高度显著（p<0.001）的下降，轻微活动对血气值也有相当大的影响（p<0.01）。然而，氧分压和氧饱和度与年龄的关系并非如先前研究所表明的那样是线性函数。为了解释动脉氧分压值或定义低氧血症，应仅使用与年龄和活动相关的正常参考值。在老年人中，经常会出现低水平的PaO2。氧饱和度的测定可能会有所帮助，特别是在区分正常和病理状态时。
