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[伴有红白血病血象的巨幼细胞性维生素B₁₂缺乏贫血]

[Megaloblastic vitamin B 12 deficiency anemia with erythroleukemic blood picture].

作者信息

Kappeler R, Gubser M

出版信息

Schweiz Med Wochenschr. 1978 Apr 15;108(15):560-3.

PMID:273979
Abstract

Report on a case of severe megaloblastic anemia in a vegetarian, associated with marked erythroleukemic blood findings probably caused by infections (bronchopneumonia, asthmatic bronchitis, urinary tract infection) and severe heart failure. Successful treatment of the above mentioned complications resulted in almost complete disappearance of pathologic cells from the blood even before vitamin B12 treatment was started. With this therapy complete recovery was achieved and the signs suspect for erythroleukemia in blood and bone marrow disappeared definitively. The case also fulfilled all the criteria of pernicious anemia (Schilling's test and determination of intrinsic factor were not done).

摘要

一名素食者患严重巨幼细胞贫血的病例报告,伴有明显的红白血病血液学表现,可能由感染(支气管肺炎、哮喘性支气管炎、尿路感染)和严重心力衰竭引起。上述并发症的成功治疗导致在开始维生素B12治疗之前,血液中的病理细胞几乎完全消失。通过这种治疗实现了完全康复,血液和骨髓中疑似红白血病的体征也彻底消失。该病例也符合恶性贫血的所有标准(未进行希林试验和内因子测定)。

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