Marin F, González Quintela A, Moya M, Suárez E, de Zárraga M
Department of Endocrinology, Clinica Puerta de Hierro, Universidad Autónoma, Madrid, Spain.
Nephron. 1989;52(3):281-2. doi: 10.1159/000185658.
Three cases of pseudohyperaldosteronism produced by the application of an antihemorrhoid cream containing 9 alpha-fluoroprednisolone are reported. All three presented edema, hypokalemia and metabolic alkalosis. Two of the patients also exhibited slight arterial hypertension. This iatrogenic possibility must be ruled out in cases of hypermineralocorticoidism, thus avoiding unnecessary and costly examinations.
报告了3例因使用含9α-氟泼尼松龙的抗痔疮乳膏而导致的假性醛固酮增多症病例。所有3例均出现水肿、低钾血症和代谢性碱中毒。其中2例患者还表现出轻度动脉高血压。在原发性醛固酮增多症病例中,必须排除这种医源性可能性,从而避免不必要且昂贵的检查。