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高血压:基于人群队列的患病率及指南依从情况

High blood pressure: prevalence and adherence to guidelines in a population-based cohort.

作者信息

Walther Diana, Curjuric Ivan, Dratva Julia, Schaffner Emmanuel, Quinto Carlos, Rochat Thierry, Gaspoz Jean-Michel, Burdet Luc, Bridevaux Pierre-Olivier, Pons Marco, Gerbase Margaret W, Schindler Christian, Probst-Hensch Nicole

机构信息

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

Division of Pulmonary Medicine, Geneva University Hospitals, Geneva, Switzerland.

出版信息

Swiss Med Wkly. 2016 Jul 11;146:w14323. doi: 10.4414/smw.2016.14323. eCollection 2016.

Abstract

QUESTIONS UNDER STUDY

High blood pressure, the single leading health risk factor worldwide, contributes greatly to morbidity and mortality. This study aimed to add to the understanding of diagnosed and undiagnosed high blood pressure in Switzerland and to evaluate adherence to hypertension guidelines.

METHODS

Included were 3962 participants from the first (2001-2003) and second (2010-2011) follow-ups of the population-based Swiss Cohort Study on Air Pollution and Lung and Heart Disease in Adults. High blood pressure was defined as blood pressure ≥140/90 mm Hg and the prevalence of doctor-diagnosed hypertension was based on questionnaire information.

RESULTS

High blood pressure was found in 34.9% of subjects, 49.1% of whom were unaware of this condition; 30.0% had doctor-diagnosed hypertension and, although 82.1% of these received drug treatments, in only 40.8% was blood pressure controlled (<140/90 mm Hg). Substantial first-line beta-blocker use and nonadherence to comorbidity-specific prescription guidelines were observed and remained mostly unexplained. Age-adjusted rates of unawareness and uncontrolled hypertension were more than 20% higher than in the USA.

CONCLUSIONS

There is room for improvement in managing hypertension in Switzerland. Population-based observational studies are essential for identifying and evaluating unmet needs in healthcare; however, to pinpoint the underlying causes it is imperative to facilitate linkage of cohort data to medical records.

摘要

研究问题

高血压是全球首要的单一健康风险因素,对发病率和死亡率有重大影响。本研究旨在增进对瑞士已诊断和未诊断高血压的了解,并评估对高血压指南的遵循情况。

方法

纳入了来自瑞士成人空气污染与心肺疾病队列研究首次随访(2001 - 2003年)和第二次随访(2010 - 2011年)的3962名参与者。高血压定义为血压≥140/90 mmHg,医生诊断高血压的患病率基于问卷调查信息。

结果

34.9%的受试者患有高血压,其中49.1%的人未意识到自己患有此病;30.0%的人被医生诊断为高血压,尽管这些人中82.1%接受了药物治疗,但只有40.8%的人的血压得到控制(<140/90 mmHg)。观察到大量使用一线β受体阻滞剂且未遵循特定合并症的处方指南,且大多无法解释原因。年龄调整后的未意识到高血压和未控制高血压的发生率比美国高出20%以上。

结论

瑞士在高血压管理方面仍有改进空间。基于人群的观察性研究对于识别和评估医疗保健中未满足的需求至关重要;然而,要查明根本原因,必须促进队列数据与医疗记录的关联。

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